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Anandamide in Health and Disease cover

Anandamide in Health and Disease

by Bernard Le Foll

1st Edition

Publisher: Academic Press

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Neuroscience

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Book Details

Print ISBN9780443190810
eText ISBN9780443302565
PublisherAcademic Press
Publishing Year2024
Edition1st Edition
LanguageEnglish
Pages566

The 1st Edition of Anandamide in Health and Disease, edited by Bernard Le Foll, provides a reference work focused on endocannabinoid signaling in physiological function and disease. Intended for biological and biomedical sciences researchers at the PhD level and above, the volume begins by explaining fundamental background biology, cellular regulation, biosynthesis, enzymatic degradation, and physiological modulation of anandamide.

The text organizes its chapters into two distinct main sections, advancing from basic cellular mechanisms to clinical disease applications. The thematic arcs encompass psychiatric conditions including mood disorders, anxiety disorders, and psychosis, while also addressing substance use disorders and underlying neurochemical pathways.

Highlighting specific disease mechanisms, Luke J. Ney and Allison Matthews contribute a chapter detailing anandamide's role in stress, fear, and PTSD. The resulting reference equips specialized researchers with a grounded summary of endocannabinoid signaling alterations across psychiatric and physical health contexts.

Table of Contents

  1. Chapter 1: Regulation of the levels of anandamide and its bioactive congeners by biosynthesis and degradation

  2. Chapter 2: Imaging the endocannabinoid enzyme fatty acid amide hydrolase in the living human brain

  3. Chapter 3: Anandamide: From modulation of neuronal excitation to antimicrobial activities--What is in common?

  4. Chapter 4: Anandamide and mood disorders

  5. Chapter 5: Anandamide and anxiety

  6. Chapter 6: Anandamide and disease. Role in stress, fear, and PTSD

  7. Chapter 7: Anandamide in disease: Role in psychosis

  8. Chapter 8: Anandamide in personality disorders

  9. Chapter 9: A brief review of anandamide in cannabis use and cannabis use disorder

  10. Chapter 10: Anandamide signaling dysfunction in the development of alcohol use disorders

  11. Chapter 11: Role of Anandamide in Nicotine Addiction

  12. Chapter 12: The role of anandamide in the sleep--wake cycle

  13. Chapter 13: Anandamide in disease: The good and bad in epilepsy

  14. Chapter 14: Role of anandamide in Alzheimer’s disease

  15. Chapter 15: The role of anandamide in digestive and defensive functions of the gut

  16. Chapter 16: The role of anandamide and the endocannabinoids in the treatment and regulation of nausea and vomiting

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