Cann's Principles of Molecular Virology
by Edward P. Rybicki
7th Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780128227848 |
| eText ISBN | 9780128227855 |
| Publisher | Academic Press |
| Publishing Year | 2023 |
| Edition | 7th Edition |
| Language | English |
| Pages | 398 |
Cann's Principles of Molecular Virology, 7th Edition, is a dedicated reference publication that introduces contemporary virological science while explaining how viruses function at a molecular level. Authored by Edward P. Rybicki, the work presents a systematic breakdown of virion particle structure interactions, host cell entry mechanisms, viral genome replication pathways, and host disease pathogenesis across biological systems.
This seventh edition incorporates targeted updates addressing contemporary developments across molecular life sciences. The expanded content encompasses clinical phage therapy applications, CRISPR functioning as a dual phage defense and offense system, broad viral evolution concepts, virus origins, and the structural biology of giant viruses.
Recognized on the 2026 Doody's Core Titles list as an essential purchase in microbiology, this volume offers targeted reference support for higher education. It assists advanced undergraduates, graduate students, and academic researchers working within virology, molecular biology, and microbiology disciplines seeking rigorous foundational analysis.
Table of Contents
Chapter 1: What are viruses, and how were they discovered?
- • Introduction
- • The history of the discovery of viruses
- • References
- • Recommended Reading
Chapter 2: Viruses and their particles
- • Viruses and their particles
- • Virions
- • References
- • Recommended reading
Chapter 3: Virus origins and genetics
- • The structure and complexity of virus genomes
- • Origins of viruses
- • From what did viruses evolve?
- • The origins of modern eukaryote viruses
- • Of ERVs and EVEs
- • The complexity of virus genomes
- • Molecular genetics
- • Virus genetics
- • The global virome
- • Epidemiology
- • Summary
- • References
- • Recommended reading
Chapter 4: Virus genomes and their replication
- • Overview of virus replication
- • Entrance into cells and viral genome replication
- • Genome replication and gene expression
- • Assembly of virions
- • Summary
- • References
- • Recommended reading
Chapter 5: Expression of virus genomes
- • Expression of genetic information
- • Virus genome coding strategies
- • Transcriptional control of expression
- • Posttranscriptional control of expression
- • Summary
- • References
- • Recommended reading
Chapter 6: Infection and immunity
- • Virus infection of prokaryotes
- • Virus infections of plants
- • Immune responses to virus infections in animals
- • Innate immune responses
- • Adaptive immune responses in vertebrates
- • RNA interference
- • Virus-host interactions
- • The course of virus infections
- • Prevention and therapy of virus infection
- • Viruses as therapeutics
- • Chemotherapy of virus infections
- • Summary
- • References
- • Recommended reading
Chapter 7: Viral pathogenesis
- • Mechanisms of cellular injury
- • Viruses and immunodeficiency
- • Acquired immunodeficiency syndrome (AIDS)
- • Virus-related diseases
- • Bacteriophages and human disease
- • Cell transformation by viruses
- • Cell transformation by retroviruses
- • Cell transformation by DNA viruses
- • Viruses and cancer
- • Summary
- • References
- • Recommended reading
Chapter 8: Panics and pandemics
- • New, emerging, and re-emerging viruses
- • Re-emerging viruses
- • Plant viruses
- • Novel human viruses
- • Zoonoses
- • Biowarfare and bioterrorism
- • Summary
- • References
- • Recommended reading
Chapter 9: Subviral agents: Deltaviruses and prions
- • Hepatitis delta virus
- • Prions
- • Molecular biology of prions
- • References
- • Recommended reading
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