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Cardiorespiratory Aspects of Duchenne Muscular Dystrophy cover

Cardiorespiratory Aspects of Duchenne Muscular Dystrophy

New Perspectives and Controversies

by David J. Birnkrant

1st Edition

Publisher: Academic Press

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Book Details

Print ISBN9780443415982
eText ISBN9780443415999
PublisherAcademic Press
Publishing Year2026
Edition1st Edition
LanguageEnglish
Pages168

Cardiorespiratory Aspects of Duchenne Muscular Dystrophy, 1st Edition, edited by David J. Birnkrant, addresses clinical care, drug development, and regulatory approval pathways for Duchenne muscular dystrophy from a cardiorespiratory perspective. Published by Academic Press, this publication provides structured material intended for clinicians, researchers, regulators, patients, and caregivers.

The volume synthesizes clinical management themes to evaluate both achievements and limitations in care for individuals with Duchenne muscular dystrophy. It covers respiratory management, cardiac care standards, and sleep complications, while presenting practical solutions for common respiratory challenges. Additional clinical sections discuss anesthetic strategies and palliative care approaches designed to support patient management.

Beyond routine intervention, the text examines therapeutic assessment methodologies through case studies of Eteplirsen and Elevidys. It offers clinicians clear summaries of care standards and clinical management strategies, giving healthcare teams and regulatory specialists grounded reference material to evaluate cardiorespiratory outcomes.

Table of Contents

  1. Chapter 1: Respiratory Management and Standards of Care

  2. Chapter 2: Cardiac Management and Standards of Care

  3. Chapter 3: The Sleep Complications of Duchenne Muscular Dystrophy

  4. Chapter 4: Challenges in Managing the Patient with Advanced Duchenne Muscular Dystrophy and an Upper Respiratory Infection

  5. Chapter 5: Practical Solutions to Common Respiratory Challenges

  6. Chapter 6: Anesthetic Strategies and Challenges

  7. Chapter 7: Palliative Care for Individuals with Duchenne Muscular Dystrophy

  8. Chapter 8: Potential Flaws in the Use of Historical Controls and Threshold Measures of Pulmonary Function

  9. Chapter 9: Additional Flaws in use of FVC % Predicted as an Outcome Measure and Proposed Improvements Based on Rideau Plots

  10. Chapter 10: Cardiorespiratory Phenotypic Variability

  11. Chapter 11: Cardiorespiratory Phenotypic Discordance and the Need for Cardiac Outcome Measures

  12. Chapter 12: Problems With the Accelerated Approval Pathway of FDA

  13. Chapter 13: Case Study of Eteplirsen

  14. Chapter 14: Case Study of Elevidys

  15. Chapter 15: The Post-Approval Journey of Eteplirsen

  16. Chapter 16: The Post-Approval Journey of Elevidys

  17. Chapter 17: Afterword

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▶Research Sources (17)
  • Cardiorespiratory Aspects of Duchenne Muscular Dystrophy eBook ...
  • [PDF] Cardiorespiratory Aspects of Duchenne Muscular Dystrophy ...
  • Cardiorespiratory Aspects of Duchenne Muscular Dystrophy - E-bok ...
  • Life sciences print books and ebooks - page 57 | Elsevier | Elsevier ...
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  • Books - Knot & Thread
  • Cardiorespiratory Aspects of Duchenne Muscular Dystrophy
  • Bound To Stay Bound Books, Inc. - Bookstore
  • Life sciences print books and ebooks - page 53 | Elsevier | Elsevier ...
  • emerging therapies, neuromuscular genetics, and new clinical challenges
  • Cardiorespiratory Aspects of Duchenne Muscular Dystrophy
  • [PDF] Neuromuscular aspects of Duchenne Muscular Dystrophy
  • Breathing Exercises in Duchenne Muscular Dystrophy: 8 Helpful Tips
  • Cardiorespiratory management of Duchenne muscular dystrophy
  • [PDF] Current Standards and Future Directions of Duchenne Muscular ...
  • (PDF) Cardiorespiratory management of Duchenne muscular dystrophy
  • [PDF] Duchenne Muscular Dystrophy Fact Sheet

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