Directed C-H Bond Functionalization

Directed C-H Bond Functionalization: Concepts and Applications, 1st Edition, provides a comprehensive reference focused on selective and efficient carbon-hydrogen bond functionalization using directing groups. Authors Debabrata Maiti and Supriya Rej present systematic catalytic strategies designed to assist academic and industrial researchers with the strategic planning of complex molecular transformations.

The text introduces the early history of carbon-hydrogen bond activation and its discovery before examining modern reaction protocols. Major thematic sections detail in-built functional group-directed reactions, proximal bond functionalization, and template-assisted distal carbon-hydrogen bond activation. The work also emphasizes transient-directing group-assisted functionalization and bifunctional non-covalent template mechanisms.

Additional topics explore advanced redox catalytic methods and metal-free directed functionalization reactions for synthetic applications. Released by Wiley-VCH as a 576-page reference volume, this text supports synthetic chemists and researchers active in organic synthesis, catalysis, medicinal chemistry, process chemistry, sustainable chemistry, and modern pharmaceutical drug design.