Drug Targeting Complexity

The 1st Edition of Drug Targeting Complexity: Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy provides a structured analysis of organ-level immune mechanisms for targeted oncology. Published by Academic Press and edited by Lalit Kumar, Dalapathi Gugulothu, and Sushama Talegaonkar, this book supports pharmaceutical researchers and pharmacologists investigating site-specific therapeutic interventions in oncology.

The volume details organ-level regulatory targets across anatomical sites including the brain, lungs, liver, skin, and bones. It assesses primary regulatory molecules such as TGF-β, CTLA-4, and IL-10, while outlining regulatory T cell mediators operating in distinct tissues such as the adrenal gland and lymph nodes.

Subsequent chapters examine tumor-specific targets across gastric, ovarian, prostate, and colon cancers. Concluding sections survey precision medicine, human genetic mutation-based targeting, nanotechnology in drug delivery, and the role of the microbiome in cancer immunotherapy. The 646-page volume offers a comprehensive reference for advanced drug discovery teams.