
Dubois' Lupus Erythematosus and Related Syndromes
by Daniel J. Wallace, Bevra Hahn
10th Edition
Publisher: Elsevier
Book Details
| Print ISBN | 9780323932325 |
| eText ISBN | 9780323933490 |
| Publisher | Elsevier |
| Publishing Year | 2024 |
| Edition | 10th Edition |
| Language | English |
| Pages | 816 |
Dubois' Lupus Erythematosus and Related Syndromes, 10th Edition, edited by Dr. Daniel J. Wallace and Dr. Bevra Hahn, delivers a comprehensive clinical reference for systemic lupus erythematosus and related connective tissue disorders. Built to support rheumatologists, internal medicine practitioners, and rheumatologists in training, the text addresses complex diagnostic and therapeutic challenges encountered in clinical practice.
The tenth edition expands its clinical focus to address key organ systems and systemic interactions. It introduces a new dedicated chapter examining the endocrine system and hormones. Additionally, the volume includes distinct new chapters that address cardiac manifestations alongside separate coverage of pulmonary manifestations in lupus patients.
To support practitioners treating diverse patient populations, the reference incorporates expertise from international contributors across 30 countries. These authors provide global perspectives on clinical manifestations, diagnostic approaches, and treatment strategies, offering practical utility for both experienced clinicians and medical fellows.
Table of Contents
Chapter 1: History of Lupus
Chapter 2: Definition and Classification of Lupus and Lupus-Related Disorders
Chapter 3: The Epidemiology of Lupus
Chapter 4: Overview of Lupus Pathogenesis
Chapter 5: Genetics of SLE
Chapter 6: Single Gene Defects and Autoinflammation: Relation to Lupus
Chapter 7: Epigenetics of Lupus
Chapter 8: The Role of the Environment and Microbiome in Lupus
Chapter 9: The Innate Immune System in SLE
Chapter 10: B Cells and Generation of Antibodies
Chapter 11: T cells
Chapter 12: Immunoregulatory Cells and Networks in Lupus
Chapter 13: Cytokines in Lupus
Chapter 14: Metabolic Control of Immunopathogenesis in Systemic Lupus Erythematosus
Chapter 15: Animal Models of Systemic Lupus Erythematosus (SLE)
Chapter 16: Abnormalities in Clearance of Immune Complexes and Dying Cells in Lupus
Chapter 17: Complement and Systemic Lupus Erythematosus
Chapter 18: Apoptosis and Inflammatory Forms of Cell Death
Chapter 19: Tissue Damage in Lupus: Free Radicals and Fibrosis
Chapter 20: Lupus Nephritis
Chapter 21: Pathogenesis of Accelerated Atherosclerosis and Vascular Injury in Systemic Lupus Erythematosus
Chapter 22: Pathogenesis of Cutaneous Lupus
Chapter 23: Pathogenesis of Neuropsychiatric Lupus
Chapter 24: Pathogenesis of Sjögren Syndrome
Chapter 25: Antinuclear Antibodies, Antibodies to DNA, Histones, and Nucleosomes
Chapter 26: Antibodies Against Extractable Nuclear Antigens (RNP, Sm, SS-A/Ro, and SS-B/La)
Chapter 27: Other Autoantibodies: Antibodies to C1q, Lipoprotein, and Endothelial Cells
Chapter 28: Pathogenesis of Antiphospholipid Antibody Syndrome
Chapter 29: Drug-Induced Lupus
Chapter 30: Overview and Clinical Presentation
Chapter 31: Skin Disease in Cutaneous Lupus Erythematosus
Chapter 32: The Musculoskeletal System and Bone Metabolism
Chapter 33: Lupus and the Cardiovascular System
Chapter 34: Pulmonary Manifestations of Systemic Lupus Erythematosus
Chapter 35: Lupus and the Nervous System: Clinical Presentation, Diagnosis, and Treatment
Chapter 36: Gastrointestinal and Hepatic Manifestations
Chapter 37: The Gut Microbiome and Lupus Pathogenesis
Chapter 38: Hematologic and Lymphoid Abnormalities in SLE
Chapter 39: Neonatal Lupus: Pathogenesis and Clinical Approaches
Chapter 40: Pregnancy and Reproductive Health Issues in Systemic Lupus Erythematosus
Chapter 41: Systemic Lupus Erythematosus in Childhood and Adolescence
Chapter 42: Clinical Aspects of Antiphospholipid Syndrome
Chapter 43: Lupus and Infections
Chapter 44: Ocular, Aural, and Oral Manifestations of Lupus
Chapter 45: Clinical Aspects of Sjögren’s Disease
Chapter 46: Clinical Presentations of Lupus in the Kidney and Urogenital System
Chapter 47: The Endocrine System and Hormones in Lupus
Chapter 48: Clinical Application of Serologic Tests, Serum Protein Abnormalities, and Other Laboratory Tests in Systemic Lupus Erythematosus
Chapter 49: Differential Diagnosis and Disease Associations
Chapter 50: Incomplete Lupus, Undifferentiated Connective Tissue Disease, and Mixed Connective Tissue Disease
Chapter 51: Clinical Markers, Metrics, Indices, and Clinical Trials
Chapter 52: Principles of Therapy, Local Measures, and NSAIDs
Chapter 53: Antimalarial Medications
Chapter 54: Systemic Glucocorticoid Therapy for SLE
Chapter 55: Immunosuppressive Drug Therapy
Chapter 56: Complementary and Integrative Health Approaches
Chapter 57: Specialized and Niche Therapies
Chapter 58: Adjunctive and Preventive Measures
Chapter 59: Management of Cutaneous Lupus Erythematosus
Chapter 60: Targeted Therapies in SLE
Chapter 61: Management of Lupus Nephritis
Chapter 62: Management of Sjögren Disease Syndrome
Chapter 63: Socioeconomics, Disparities, and Disability
Chapter 64: Prognosis and Mortality of Systemic Lupus Erythematosus
Chapter 65: Future Directions: Therapeutics
Chapter 66: Expanding the Opportunities to Effectively Treat Patients: Clinical Considerations
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