Endocrine Disruption and Human Health
by Philippa D. Darbre
2nd Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780128219850 |
| eText ISBN | 9780128219881 |
| Publisher | Academic Press |
| Publishing Year | 2021 |
| Edition | 2nd Edition |
| Language | English |
| Pages | 538 |
Endocrine Disruption and Human Health, 2nd Edition, introduces endocrine-disrupting chemicals, their sources in the ecosystem, and their impact on human biology. Edited by Philippa D. Darbre, the volume brings together specialist contributions that connect basic molecular mechanisms with public health concerns.
The text examines how environmental chemicals interfere with hormone signaling, the assay systems used to evaluate these exposures, and the resulting risks to organ systems across the lifespan. It also reviews risk assessment procedures and regulatory approaches for managing chemical exposures.
Selected for Doody's Core Titles 2024 in Endocrinology/Metabolic Disease, this reference serves academic, clinical, and biomedical researchers, health professionals, graduate students, and advanced undergraduates in public health and toxicology.
Table of Contents
SECTION 1: OVERVIEW and SCOPE
Chapter 1: What is endocrine disruption?
Chapter 2: Which chemicals are endocrine disruptors?
SECTION 2: MECHANISMS and ASSAY SYSTEMS
Chapter 3: Environmental oestrogens: Disrupters of oestrogen action
Chapter 4: Disrupters of androgen action
Chapter 5: Assay systems for studying endocrine disruption
Chapter 6: Non-monotonic responses in endocrine disruption
Chapter 7: Endocrine disrupters as modifiers of endogenous hormone synthesis
SECTION 3: CONCERNS FOR HUMAN HEALTH
Chapter 8: Endocrine disruption and female reproductive health
Chapter 9: Endocrine disruption and breast cancer
Chapter 10: Endocrine disruption and male reproductive health
Chapter 11: Endocrine disruption and prostate cancer
Chapter 12: Endocrine disruption and thyroid disease
Chapter 13: Endocrine disruption of adrenal function
Chapter 14: Endocrine disruption of developmental pathways and children’s health
Chapter 15: Endocrine disruption of immune function
Chapter 16: Endocrine disruption and obesity, metabolic syndrome and type 2 diabetes
Chapter 17: Endocrine disruption and cardiovascular disease
Chapter 18: Transgenerational effects of endocrine disruption
Chapter 19: Regulatory considerations
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