Epigenetic Cancer Therapy

Name: Epigenetic Cancer Therapy
Price: 185 USD
Availability: InStock
ISBN: 9780323913676

by Steven Gray

2nd Edition

Publisher: Academic Press

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Oncology

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Book Details

Print ISBN	9780323913676
eText ISBN	9780323917155
Publisher	Academic Press
Publishing Year	2023
Edition	2nd Edition
Language	English
Pages	772

The 2nd Edition of Epigenetic Cancer Therapy, edited by Steven Gray, examines foundational chromatin mechanisms and therapeutic intervention strategies across contemporary molecular oncology. Built specifically for researchers in genetics, molecular biology, and oncology, this reference volume establishes how targeted molecular modifications disrupt aberrant gene expression patterns and restore regulatory control in malignant cells.

Core thematic sections detail therapeutic applications of epigenetic machinery designed to eradicate persistent cancer stem cells. The coverage incorporates recent technological advances, including CRISPR/Cas9 mediated approaches, CAR-T based therapies, oncohistones, and single-cell epigenetic analysis, alongside findings linking environmental pollution to epigenetic changes during tumor development.

Published in 2023 by Academic Press as part of the Translational Epigenetics series, this 772-page reference offers pharmaceutical science and clinical therapy specialists structured analysis of emerging small-molecule targets. The material equips investigative teams with factual grounding to evaluate personalized treatment strategies.

Chapter 1: Introduction
Chapter 2: DNA Methylation and Hydroxymethylation in Cancer
Chapter 3: Writers, Readers, and Erasers of Epigenetic Marks
Chapter 4: Oncohistones
Chapter 5: MicroRNAs, epi-miRNAs and Cancer
Chapter 6: Long Noncoding RNAs and Cancer
Chapter 7: The Epitranscriptome
Chapter 8: Mining the Epigenetic Landscape: Surface Mining or Deep Underground - Alecsandar Milosavljevic
Chapter 9: Epigenetics Clocks: Concepts for Carcinogenesis
Chapter 10: Environmental Pollution Epigenetics and Cancer
Chapter 11: Development of Epigenetic Targeted Therapies in Hematological Malignancies: From Serendipity to Synthetic Lethality
Chapter 12: Epigenetic Therapy in Lung Cancer
Chapter 13: Breast Cancer Epigenetics
Chapter 14: Therapeutic Applications of the Prostate Cancer Epigenome
Chapter 15: Neuroblastoma
Chapter 16: Nutritional Epigenetic Regulators in the Field of Cancer: New Avenues for Chemopreventive Approaches -
Chapter 17: Emerging Epigenetic Therapies- Lysine Methyltransferase/PRC Complex Inhibitors
Chapter 18: Inhibitors of Jumonji C-Domain Histone Demethylases
Chapter 19: Emerging Epigenetic Therapies: Lysine Acetyltransferase Inhibitors
Chapter 20: Histone Deacetylases
Chapter 21: Emerging Epigenetic Therapies
Chapter 22: Genetic Intratumoral Heterogeneity
Chapter 23: Challenges for single cell epigenetic analysis
Chapter 24: Epigenetics Underpinning DNA Damage Repair
Chapter 25: Epigenetics of Cisplatin Resistance
Chapter 26: Therapeutically Targeting Epigenetic Regulation of Cancer Stem Cells
Chapter 27: Personalized Epigenetic Therapy-Chemosensitivity Testing
Chapter 28: Personalized Therapy-Epigenetic Profiling as Predictors of Prognosis and Response
Chapter 29: Epigenetic Priming - Fact or Fallacy
Chapter 30: CRISPR and epigenetics
Chapter 31: Epigenetics and CAR-T