Epigenetic Regulations in Gastrointestinal Cancers

Name: Epigenetic Regulations in Gastrointestinal Cancers
Price: 175 USD
Availability: InStock
ISBN: 9780443277658

by Ganji Purnachandra Nagaraju, Seema Kumari

1st Edition

Publisher: Academic Press

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Oncology

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Book Details

Print ISBN	9780443277658
eText ISBN	9780443277665
Publisher	Academic Press
Publishing Year	2026
Edition	1st Edition
Language	English

Epigenetic Regulations in Gastrointestinal Cancers, 1st Edition, examines how genomic and epigenomic alterations drive tumor development across the digestive tract. Designed for researchers in oncology, molecular biology, epigenetics, and pharmacology, alongside practicing clinicians, this book provides a structured evaluation of the molecular mechanisms governing gastrointestinal malignancies.

The text synthesizes scientific research detailing how the tumor microenvironment and cellular signaling pathways influence gastrointestinal cancer neoplasia. Readers analyze established strategies for identifying specific epigenetic targets while evaluating approaches to overcome treatment resistance. Additional coverage highlights the biological roles of non-coding RNAs, functional peptides encoded by non-coding RNA, and exosome-derived biomarkers and therapies.

Edited by Ganji Purnachandra Nagaraju and Seema Kumari, this Academic Press volume establishes a clear analytical structure for exploring complex molecular processes. It offers oncology researchers and clinical practitioners an organized resource for connecting advanced laboratory findings directly to therapeutic development.

Chapter 1: Epigenetics of GI cancers
Chapter 2: Overview of epigenetic changes in cancer-related to gastrointestinal systems
Chapter 3: Epigenetic change-based cancer development in the gastrointestinal gastric, pancreatic, and colorectal cancers
Chapter 4: Epigenetics in gastrointestinal cancers
Chapter 5: Targeting methylation and acetylation in colon cancer
Chapter 6: Epigenetics in angiogenesis, gastrointestinal cancer progression and its clinical significance
Chapter 7: Non-coding RNAs
Chapter 8: The roles of non-coding RNA-encoded functional peptides in gastrointestinal cancer
Chapter 9: Targeting methylation and acetylation in colon cancer
Chapter 10: Deciphering the crosstalk between single cell sequencing and gastrointestinal cancer
Chapter 11: Exosome-derived biomarkers and therapies
Chapter 12: Therapeutic challenges and advances in the management of colorectal cancer overcoming resistance mechanisms and exploring future directions
Chapter 13: Current and emerging epigenetic therapies and future directions
Chapter 14: Phytochemicals as epigenetic modulators in gastrointestinal cancer
Chapter 15: Epigenetics and metabolic involvement in regeneration: An overview
Chapter 16: The role of DNA methyltransferase genes in cancers: A systematic review and meta-analysis of DNMT1 and DNMT3B gene polymorphisms
Chapter 17: Epigenetic and post-transcriptional regulators of colon cancer formation vs progression invasion and metastasis
Chapter 18: Role of the microbiome on epigenetic changes in pancreatic and colon cancers
Chapter 19: DNA methylation and histone modifications in gastrointestinal cancers
Chapter 20: Epigenetic mechanisms in colorectal cancer: Preclinical studies to clinical implications
Chapter 21: DNA methylation and histone modification in liver cancer