Epigenetics in Human Disease

Name: Epigenetics in Human Disease
Price: 250 USD
Availability: InStock
ISBN: 9780443218118

by Trygve O. Tollefsbol

3rd Edition

Publisher: Academic Press

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Genetics

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Book Details

Print ISBN	9780443218118
eText ISBN	9780443218125
Publisher	Academic Press
Publishing Year	2023
Edition	3rd Edition
Language	English
Pages	1300

Epigenetics in Human Disease, 3rd Edition, edited by Trygve O. Tollefsbol, provides a comprehensive examination of molecular mechanisms that alter gene expression in human disease. Published by Academic Press, this volume establishes how non-genetic modifications influence pathological progression, biomarker identification, and targeted therapeutic interventions across clinical medicine.

The content connects foundational concepts to clinical applications across several thematic arcs, including cancer epigenetics, neurobiological disorders, autoimmune diseases, cardiovascular pathology, biological aging, and metabolic dysfunction. Chapters detail specific molecular features such as microRNA alterations, histone modifications, aberrant DNA methylation, and noncoding RNA networks involved in stem cell renewal and differentiation.

To support technical comprehension, every chapter incorporates dedicated reference features, including step-by-step methods, clear definitions, illustrative figures, formal chapter summaries, and disease research case studies. These practical components assist graduate students, advanced undergraduates, clinicians, and active researchers working in genetics, molecular biology, biology, and pharmaceutical science.

Chapter 1: Epigenetics of Human Disease: An Overview
Chapter 2: Methods and Strategies to Determine Epigenetic Variation in Human Disease
Chapter 3: DNA Methylation–Based Measures of Biological Aging
Chapter 4: Bioinformatics of Epigenomic Data Generated From Next-Generation Sequencing
Chapter 5: DNA Methylation Alterations in Human Cancer
Chapter 6: Alterations of Histone Modifications in Cancer
Chapter 7: MicroRNA in Cancer
Chapter 8: Epigenetic Approaches to Cancer Therapy
Chapter 9: Epigenetics in Neurobehavioral Disease
Chapter 10: Emerging Role of Epigenetics in Human Neurodevelopmental Disorders
Chapter 11: The Epigenetics of Alzheimer's and Other Neurodegenerative Disorders
Chapter 12: Epigenetic Modulation of Human Neurobiological Disorders
Chapter 13: Epigenetic Basis of Autoimmune Disorders in Humans
Chapter 14: Approaches to Autoimmune Diseases Using Epigenetic Therapy
Chapter 15: Epigenomics and Human Obesity
Chapter 16: Epigenetic Approaches to Control Obesity
Chapter 17: Early-Life Nutrition, Epigenetics and Prevention of Obesity
Chapter 18: Epigenetics of Diabetes in Humans
Chapter 19: The Potential of Epigenetic Compounds in Treating Diabetes
Chapter 20: Epigenetic-Processes Driven Disorders and Therapeutics
Chapter 21: Epigenetics of Allergic Diseases Allergies, Eczema, Asthma, and Rhinitis
Chapter 22: Therapy of Airway Disease: Epigenetic Potential
Chapter 23: The Role of Epigenetics in Cardiovascular Disease
Chapter 24: Epigenetic Treatment Approaches to Cardiovascular Disease
Chapter 25: Epigenetics and Human Infectious Diseases
Chapter 26: Therapy of Infectious Diseases Using Epigenetic Approaches
Chapter 27: Translational Aspects of the Endometriosis Epigenome
Chapter 28: Aberrant DNA Methylation Patterns in Gynecologic Cancers: Implications for Prevention and Therapy
Chapter 29: Epigenetics in Human Reproduction and Gynecologic Diseases
Chapter 30: Epigenetics of Transgenerational Inheritance of Disease
Chapter 31: Epigenomic Mechanisms of Human Developmental Disorders
Chapter 32: Therapeutic Approaches to Imprinting Diseases
Chapter 33: Stem Cell Epigenetics and Human Disease
Chapter 34: Noncoding RNA Regulatory Networks, Epigenetics, and Programming Stem Cell Renewal and Differentiation: Implications for Stem Cell Therapy
Chapter 35: Aging and Disease: The Epigenetic Bridge
Chapter 36: Epigenetic Programming of Human Disease and Aging
Chapter 37: Epigenetic Prospects in Epidemiology and Public Health