
Extracellular Mitochondria in Health and Disease
by Carla Lopes, Paulo César da Silva Pinheiro
1st Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780443292835 |
| eText ISBN | 9780443292842 |
| Publisher | Academic Press |
| Publishing Year | 2025 |
| Edition | 1st Edition |
| Language | English |
| Pages | 198 |
Extracellular Mitochondria in Health and Disease, 1st Edition, presents an authoritative examination of extracellular mitochondria in intercellular communication and disease pathology. Authored by Carla Lopes and Paulo César da Silva Pinheiro, this book clarifies how organelle transfer influences cell-to-cell signaling mechanisms. It caters directly to researchers, academics, and students who require a grounded overview of non-cell-autonomous mitochondrial activity.
The work synthesizes core concepts surrounding the cellular mechanisms of mitochondrial transfer, detailing how transferred organelles participate in both metabolic signaling and immune signaling. In addition, it evaluates the direct interplay and functional crosstalk that occurs between extracellular vesicles and mitochondria across healthy and perturbed biological systems.
By detailing these core biological mechanisms, the text provides structured reference material tailored for scholars in biochemistry and cellular and molecular biology. It equips readers to analyze how extracellular mitochondrial dynamics modulate broader cell communication networks.
Table of Contents
Chapter 1: General introduction
Chapter 2: Cellular mechanisms of mitochondrial transfer and metabolic and immune signaling
Chapter 3: Modern techniques for studying extracellular mitochondria and mitochondria-derived extracellular vesicles
Chapter 4: Interplay between extracellular vesicles and mitochondria
Chapter 5: Extracellular mitochondria: dual roles in neurodegeneration and neuroprotection
Chapter 6: Extracellular vesicles bearing mitochondria in cardiometabolic diseases
Chapter 7: Therapeutic potential of extracellular mitochondria: applications and challenges
Chapter 8: Conclusions and future perspectives
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