Fundamentals of Brain Organoids for Neurological Diseases

Name: Fundamentals of Brain Organoids for Neurological Diseases
Price: 165 USD
Availability: InStock
ISBN: 9780443298981

by Balachandar Vellingiri, Mahalaxmi Balachandar

1st Edition

Publisher: Academic Press

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Neuroscience

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Book Details

Print ISBN	9780443298981
eText ISBN	9780443298998
Publisher	Academic Press
Publishing Year	2025
Edition	1st Edition
Language	English
Pages	360

Fundamentals of Brain Organoids for Neurological Diseases, 1st Edition, provides a dedicated reference on generating three-dimensional tissue structures from human-induced pluripotent stem cells to model central nervous system disorders. The text guides clinical professionals and active researchers through concepts required to construct and analyze brain organoid models.

The thematic organization covers key neurodevelopmental conditions, detailing how organoids aid in investigating autism, Rett Syndrome, and bipolar disorder. Additionally, the volume addresses major neurodegenerative pathologies, focusing on organoid applications for Alzheimer's disease, Parkinson's disease, and Huntington's disease.

A defining element of the text is its focus on practical translation, highlighting drug targeting methodologies alongside active clinical trials that use brain organoids. This structured scope prepares readers in clinical and academic settings to evaluate organoid platforms across disease contexts.

Chapter 1: An overview on organoids - Past, present and future scenario of organoids
Chapter 2: A brief introduction about neurodevelopmental disorders
Chapter 3: Use of brain organoids for autism
Chapter 4: Role of brain organoids in Rett Syndrome
Chapter 5: Brain organoids in bipolar disorder: Unraveling mechanisms and therapeutic approaches
Chapter 6: Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders
Chapter 7: An overview of neurodegenerative diseases
Chapter 8: Use of brain organoids for Parkinson’s disease and Alzheimer’s disease
Chapter 9: Application of brain organoids in Huntington’s disease
Chapter 10: Ongoing clinical trials on use of brain organoids for neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, etc.)
Chapter 11: How human-induced pluripotent stem cells are derived into organoids
Chapter 12: Elements required and days involved in organoid generation
Chapter 13: Brain organoids – Challenges while constructing organoids
Chapter 14: Existing drug targeting and research using brain organoids
Chapter 15: Ethical consideration while conducting organoids research
Chapter 16: Future directions and conclusion