
Human Reproductive and Prenatal Genetics
by Peter C.K. Leung, Jie Qiao
2nd Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780323913805 |
| eText ISBN | 9780323913812 |
| Publisher | Academic Press |
| Publishing Year | 2023 |
| Edition | 2nd Edition |
| Language | English |
| Pages | 928 |
Human Reproductive and Prenatal Genetics, 2nd Edition, is an academic reference work designed to explain the biological mechanisms behind human reproduction and gestational health. Edited by Peter C.K. Leung and Jie Qiao, this publication supports active researchers and clinicians in human genetics, genomics, and reproductive medicine by examining how genomic science informs developmental biology.
The text synthesizes essential stages of cellular and physiological progression across human development. It covers the genetic control underlying reproductive tract development and gametogenesis, alongside the genetics of fertilization and embryo implantation. Further chapters examine genetic and epigenetic factors in assisted reproduction while detailing placental function during normal and abnormal pregnancies.
Selected as a Doody's Core Title for 2024 in Clinical Genetics, this edition provides a structured evidentiary framework for specialized practice. It offers reference value for gynecologists, obstetricians, andrologists, embryologists, endocrinologists, genetic counselors, bioethicists, and advanced students.
Table of Contents
Chapter 1: Developmental genetics of the male reproductive system
Chapter 2: Developmental genetics of the female reproductive tract
Chapter 3: Genetics and genomics of early gonad development
Chapter 4: Effects of aging on sperm chromatin
Chapter 5: In vitro spermatogenesis from pluripotent stem cells
Chapter 6: The molecular genetics of oogenesis
Chapter 7: Growth of the mammalian oocyte: Focus on intercellular contact and communication
Chapter 8: In vitro activation of ovarian follicles
Chapter 9: Interaction of sperm and embryo with the female reproductive tract
Chapter 10: MicroRNAs in gametes and preimplantation embryos: Clinical implications
Chapter 11: Epigenetic modifications in the human placenta
Chapter 12: In vitro models of human blastocysts and early embryogenesis
Chapter 13: microRNAs in pregnancy: Implications for basic research and clinical management
Chapter 14: Human X-chromosome inactivation: Complexity and clinical implications
Chapter 15: The intergenerational effects on fetal programming
Chapter 16: Theoretical and experimental strategies for preservation and restoration of male fertility
Chapter 17: Update on the genetics and genomics of premature ovarian insufficiency
Chapter 18: Premature ovarian insufficiency
Chapter 19: Genetics of polycystic ovary syndrome
Chapter 20: Developmental origins and genetic basis of polycystic ovary syndrome
Chapter 21: Genetic basis of metabolism and inflammation in PCOS
Chapter 22: Genetics and genomics of recurrent pregnancy loss
Chapter 23: Genetics and genomics of endometriosis
Chapter 24: Human genetics and assisted reproduction in endometriosis
Chapter 25: Uterus transplantation as an infertility treatment
Chapter 26: Impacts of COVID-19 on reproductive health and prenatal genetics
Chapter 27: Genomics in reproductive medicine: Current and future applications
Chapter 28: Molecular cytogenomics of human genetic disorders
Chapter 29: Next-generation sequencing for gene panels, clinical exome, and whole-genome analysis
Chapter 30: Chromosomal microarrays and next-generation sequencing for diagnosis of fetal abnormalities
Chapter 31: Noninvasive prenatal testing for genetic diseases
Chapter 32: Noninvasive prenatal testing/screening by circulating cell-free DNA
Chapter 33: Application of new technologies in embryos: From gene editing to synthetic embryos
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