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Human Reproductive and Prenatal Genetics cover

Human Reproductive and Prenatal Genetics

by Peter C.K. Leung, Jie Qiao

2nd Edition

Publisher: Academic Press

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Genetics

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Book Details

Print ISBN9780323913805
eText ISBN9780323913812
PublisherAcademic Press
Publishing Year2023
Edition2nd Edition
LanguageEnglish
Pages928

Human Reproductive and Prenatal Genetics, 2nd Edition, is an academic reference work designed to explain the biological mechanisms behind human reproduction and gestational health. Edited by Peter C.K. Leung and Jie Qiao, this publication supports active researchers and clinicians in human genetics, genomics, and reproductive medicine by examining how genomic science informs developmental biology.

The text synthesizes essential stages of cellular and physiological progression across human development. It covers the genetic control underlying reproductive tract development and gametogenesis, alongside the genetics of fertilization and embryo implantation. Further chapters examine genetic and epigenetic factors in assisted reproduction while detailing placental function during normal and abnormal pregnancies.

Selected as a Doody's Core Title for 2024 in Clinical Genetics, this edition provides a structured evidentiary framework for specialized practice. It offers reference value for gynecologists, obstetricians, andrologists, embryologists, endocrinologists, genetic counselors, bioethicists, and advanced students.

Table of Contents

  1. Chapter 1: Developmental genetics of the male reproductive system

  2. Chapter 2: Developmental genetics of the female reproductive tract

  3. Chapter 3: Genetics and genomics of early gonad development

  4. Chapter 4: Effects of aging on sperm chromatin

  5. Chapter 5: In vitro spermatogenesis from pluripotent stem cells

  6. Chapter 6: The molecular genetics of oogenesis

  7. Chapter 7: Growth of the mammalian oocyte: Focus on intercellular contact and communication

  8. Chapter 8: In vitro activation of ovarian follicles

  9. Chapter 9: Interaction of sperm and embryo with the female reproductive tract

  10. Chapter 10: MicroRNAs in gametes and preimplantation embryos: Clinical implications

  11. Chapter 11: Epigenetic modifications in the human placenta

  12. Chapter 12: In vitro models of human blastocysts and early embryogenesis

  13. Chapter 13: microRNAs in pregnancy: Implications for basic research and clinical management

  14. Chapter 14: Human X-chromosome inactivation: Complexity and clinical implications

  15. Chapter 15: The intergenerational effects on fetal programming

  16. Chapter 16: Theoretical and experimental strategies for preservation and restoration of male fertility

  17. Chapter 17: Update on the genetics and genomics of premature ovarian insufficiency

  18. Chapter 18: Premature ovarian insufficiency

  19. Chapter 19: Genetics of polycystic ovary syndrome

  20. Chapter 20: Developmental origins and genetic basis of polycystic ovary syndrome

  21. Chapter 21: Genetic basis of metabolism and inflammation in PCOS

  22. Chapter 22: Genetics and genomics of recurrent pregnancy loss

  23. Chapter 23: Genetics and genomics of endometriosis

  24. Chapter 24: Human genetics and assisted reproduction in endometriosis

  25. Chapter 25: Uterus transplantation as an infertility treatment

  26. Chapter 26: Impacts of COVID-19 on reproductive health and prenatal genetics

  27. Chapter 27: Genomics in reproductive medicine: Current and future applications

  28. Chapter 28: Molecular cytogenomics of human genetic disorders

  29. Chapter 29: Next-generation sequencing for gene panels, clinical exome, and whole-genome analysis

  30. Chapter 30: Chromosomal microarrays and next-generation sequencing for diagnosis of fetal abnormalities

  31. Chapter 31: Noninvasive prenatal testing for genetic diseases

  32. Chapter 32: Noninvasive prenatal testing/screening by circulating cell-free DNA

  33. Chapter 33: Application of new technologies in embryos: From gene editing to synthetic embryos

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