Janeway's Immunobiology

Published by W. W. Norton & Company, Janeway's Immunobiology, 10th Edition, is a foundational textbook designed to explain host defense mechanisms for advanced undergraduate, graduate, and medical school students. Written by Kenneth M. Murphy, Casey Weaver, and Leslie J. Berg, this volume establishes how the immune system identifies, responds to, and eliminates pathogenic threats.

The core material follows a clear thematic progression through molecular and cellular immunology. Early chapters examine innate immunity, antigen recognition by B-cell and T-cell receptors, and lymphocyte development. Subsequent sections detail T cell-mediated responses, humoral immunity, and barrier immune systems, leading into host defense failures, hypersensitivity, autoimmunity, and immune response manipulation.

To reflect recent scientific discoveries, the Tenth Edition incorporates updated research on SARS-CoV-2 and the cGAS/STING signaling pathway. Visual explanations throughout the text are strengthened by an updated illustration program containing 88 new figures, helping students visualize complex biological interactions across cellular environments.