Method Development in Analytical HPLC

Method Development in Analytical HPLC, 1st Edition, provides systematic technical direction for creating and refining liquid chromatography procedures. Authored by Serban C. Moldoveanu and Victor David, the book opens with introductory concepts in chemical analysis to guide readers through establishing sound chromatographic methods.

The volume explores major chromatographic separation modes, covering reversed-phase HPLC, hydrophilic interaction liquid chromatography, ion exchange chromatography, size exclusion chromatography, and chiral chromatography. Dedicated emphasis is placed on detection techniques using mass spectrometry to evaluate chromatographic separation and performance.

To address modern operational priorities, the text examines green chemistry applications alongside computer-assisted method development techniques. This work supports graduate students and researchers practicing analytical chemistry across industrial, academic, and government research settings.