OrthoBiologics
by Rachel M. Frank, Jorge Chahla, Garrett Jackson
1st Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780128229026 |
| eText ISBN | 9780128229033 |
| Publisher | Academic Press |
| Publishing Year | 2024 |
| Edition | 1st Edition |
| Language | English |
| Pages | 280 |
The 1st Edition of OrthoBiologics provides a single-source reference outlining biologic therapies for orthopaedic conditions. Developed for orthopaedic surgeons, sports medicine specialists, rheumatologists, physiatrists, clinical researchers, and medical students, this text defines foundational biological principles and their practical application in patient care.
The volume examines diverse autologous and allogeneic options. Chapters detail platelet-rich plasma and platelet-poor plasma alongside methods for measurement and optimization. Further chapters evaluate bone marrow aspirate, bone marrow aspirate concentrate, and adipose mesenchymal stromal cells, extending to synovial mesenchymal stem cells, peripheral blood stem cells, and amniotic membrane-derived allografts.
Edited by Rachel M. Frank, Jorge Chahla, and Garrett Jackson, the text incorporates growth factors, signaling mediators, and bioscaffolds for knee osteochondral injuries. It concludes with administration workflows in procedure rooms and operating rooms, evolving regulatory restrictions, and treatment complications, matching the reference needs of clinical specialists and scholars.
Table of Contents
Chapter 1: Autologous blood; platelet-rich plasma and platelet-poor plasma
Chapter 2: Defining, measuring and optimizing platelet-rich plasma
Chapter 3: Optimal use of platelet-rich plasma and plateletpoor plasma
Chapter 4: Where orthobiologics started: what are mesenchymal stem cells?
Chapter 5: Bone marrow-derived mesenchymal stromal cells
Chapter 6: Defining, optimizing, and measuring bone marrow aspirate and bone marrow concentrate
Chapter 7: Optimal clinical use of bone marrow aspirate and bone marrow aspirate concentrate
Chapter 8: Adipose mesenchymal stromal cells
Chapter 9: Defining, optimizing, measuring, and utilizing adipose, MFAT, etc.
Chapter 10: Optimal clinical use of adipose mesenchymalstromal cells
Chapter 11: Basic science and preclinical evidence for amniotic membrane2derived allografts in
Chapter 12: Defining, optimizing, and measuring amniotic/ placental mesenchymal stem cells
Chapter 13: Optimal clinical use of amniotic/placental mesenchymal stem cells
Chapter 14: Synovial mesenchymal stem cells
Chapter 15: Peripheral blood stem cells
Chapter 16: Orthobiologics—growth factors and mediators
Chapter 17: Orthobiologics in the procedure room—who, what, where, when, and how
Chapter 18: Orthobiologics in the operating room—who, what, where, when, and how
Chapter 19: The changing regulatory environment: regulations and restrictions
Chapter 20: Bioscaffolds for osteochondral injuries of the knee
Chapter 21: Orthobiologics on the horizon
Chapter 22: Complications associated with orthobiologics
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- OrthoBiologics - Rachel M. Frank, Jorge Chahla, Garrett Jackson
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