
Book Details
| Print ISBN | 9780443238024 |
| eText ISBN | 9780443238031 |
| Publisher | Academic Press |
| Publishing Year | 2024 |
| Edition | 2nd Edition |
| Language | English |
| Pages | 780 |
Personalized Epigenetics, 2nd Edition, edited by Trygve Tollefsbol and published by Academic Press, provides an exhaustive reference on human epigenetic variation for university researchers, graduate students, and postgraduates. Published within the Translational Epigenetics book series, this publication establishes how molecular differences between individuals shape targeted scientific investigations and clinical interventions.
The volume organizes its foundational science around inter-individual variability, specifically examining DNA methylation, histone modifications, and noncoding RNA profiles. It connects these fundamental biological mechanisms to specialized domains including epigenetic biomarkers, epigenetic technology platforms, personalized toxicology, environmental contaminant interactions, and nutriepigenomics.
Further chapters address applied clinical disciplines such as personalized pharmacoepigenomics, epigenetic drug development, personalized pain management, and forensic epigenetics. The volume also examines the epigenetic fingerprint alongside technology methods for analyzing methylation variations. This 780-page work supports upper-level university research settings as well as professional environments across health care, pharmaceutical, and biotechnology organizations.
Table of Contents
Chapter 1: Epigenetics of Personalized Medicine
Chapter 2: Interindividual Variability of DNA Methylation
Chapter 3: Differences in Histone Modifications Between Individuals
Chapter 4: Individual Noncoding RNA Variations
Chapter 5: Personalized Epigenetics: Analysis and Interpretation of DNA Methylation Variation
Chapter 6: Limitations of Personalized Epigenetic Variation Comparisons
Chapter 7: Personalized Epigenetics Technologies
Chapter 8: Computational Methods in Epigenetics
Chapter 9: Epigenetic Biomarkers in Personalized Medicine
Chapter 10: Epigenetic ‘Fingerprint’
Chapter 11: Epigenetics of Personalized Toxicology
Chapter 12: Environmental Contaminants and Their Relationship to the Epigenome
Chapter 13: Nutriepigenomics: Personalized Nutrition Meets Epigenetics
Chapter 14: Personalized Pharmacoepigenomics
Chapter 15: Epigenetics of Personalized Nanomedicine
Chapter 16: Personalized Medicine and Epigenetic Drug Development
Chapter 17: Understanding Interindividual Epigenetic Variations in Obesity and Its Management
Chapter 18: Personalized Epigenetic Management of Diabetes
Chapter 19: Epigenetics and Personalized Pain Management
Chapter 20: Epigenetic Modification of miRNAs in Cancer
Chapter 21: Epigenetics and Chemoresistance: A Personalized Approach to Cancer Therapy
Chapter 22: Personalized Epigenetics and Neurological Disorders
Chapter 23: Managing Autoimmune Disorders through Personalized Epigenetic Approaches
Chapter 24: Cardiovascular Diseases and Personalized Epigenetics
Chapter 25: Future Challenges and Prospects for Personalized Epigenetics
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