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Principles and Practice of Sleep Medicine cover

Principles and Practice of Sleep Medicine

by Meir Kryger, Thomas Roth, William Dement

6th Edition

Publisher: Elsevier

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Sleep Medicine

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Book Details

Print ISBN9780323242882
eText ISBN9780323377515
PublisherElsevier
Publishing Year2017
Edition6th Edition
LanguageEnglish
Pages1730

Principles and Practice of Sleep Medicine, 6th Edition, provides comprehensive, evidence-based guidance across the spectrum of sleep disorders. The reference helps practitioners evaluate sleep pathology and make informed clinical decisions.

The volume addresses normal sleep and its variance, chronobiology, and the genetic and genomic foundations of sleep. It also examines clinical pharmacology, detailing the actions of hypnotic medications alongside applied disciplines such as occupational sleep medicine.

Designed for sleep specialists, pulmonologists, and neurologists, this full-color text serves as a preparation resource for the sleep medicine fellowship examination. The 2017 edition includes extensive online material to support clinical practice.

Table of Contents

  1. Section 1: Normal Sleep and Its Variance

  2. Chapter 1: History of Sleep Physiology and Medicine

  3. Chapter 2: Normal Human Sleep: An Overview

  4. Chapter 3: Normal Aging

  5. Chapter 4: Daytime Sleepiness and Alertness

  6. Chapter 5: Sleep Deprivation

  7. Chapter 6: Genetics of Normal Human Sleep

  8. Section 2: Sleep Mechanisms and Phylogeny

  9. Chapter 7: Neural Control of Sleep in Mammals

  10. Chapter 8: Rapid Eye Movement Sleep

  11. Chapter 9: Novel Techniques for identifying Sleep Mechanisms and Disorders

  12. Chapter 10: Sleep in Animals: A State of Adaptive Inactivity

  13. Section 3: Physiology in Sleep

  14. Chapter 11: Relevance of Sleep Physiology for Sleep Medicine Clinicians

  15. Chapter 12: What Brain Imaging Reveals about Sleep Generation and Maintenance?

  16. Chapter 13: Cardiovascular Physiology and Coupling with Respiration: Central and Autonomic Regulation

  17. Chapter 14: Cardiovascular Physiology: Autonomic Control in Health and in Sleep Disorders

  18. Chapter 15: Respiratory Physiology: Central Neural Control of Respiratory Neurons and Motoneurons during Sleep

  19. Chapter 16: Respiratory Physiology: Understanding the Control of Ventilation

  20. Chapter 17: Physiology of Upper and Lower Airways

  21. Chapter 18: Respiratory Physiology: Sleep at High Altitudes

  22. Chapter 19: Sleep and Host Defense

  23. Chapter 20: Endocrine Physiology in Relation to Sleep and Sleep Disturbances

  24. Chapter 21: Thermoregulation in Sleep and Hibernation

  25. Chapter 22: Memory Processing in Relation to Sleep

  26. Chapter 23: Sensory and Motor Processing During Sleep and Wakefulness

  27. Chapter 24: Opiate Action on Sleep and Breathing

  28. Chapter 25: Pathophysiology of Sleep-wake Disturbances After Traumatic Brain Injury

  29. Section 4: Genetics and Genomic Basis of Sleep

  30. Chapter 26: Introduction: Genetics and Genomics of Sleep

  31. Chapter 27: Genetics and Genomics of Circadian Clocks

  32. Chapter 28: Genetics and Genomic Basis of Sleep in Simple Model Organisms

  33. Chapter 29: Genetics and Genomic Basis of Sleep in Rodents

  34. Chapter 30: Genetics and Genomic Basis of Sleep in Healthy Humans

  35. Chapter 31: Genetics and Genomic Basis of Sleep Disorders in Humans

  36. Section 5: Chronobiology

  37. Chapter 32: Introduction: Master Circadian Clock and Master Circadian Rhythm

  38. Chapter 33: Anatomy of the Mammalian Circadian System

  39. Chapter 34: Physiology of the Mammalian Circadian System

  40. Chapter 35: Human Circadian Timing System and Sleep-Wake Regulation

  41. Chapter 36: Sleep Homeostasis and Models of Sleep Regulation

  42. Chapter 37: Circadian Rhythms in Sleepiness, Alertness, and Performance

  43. Chapter 38: Central and Peripheral Circadian Clocks

  44. Chapter 39: Circadian Dysregulation and Mental and Physical Health

  45. Chapter 40: Circadian Disorders of the Sleep-Wake Cycle

  46. Section 6: Pharmacology

  47. Chapter 41: Hypnotic Medications: Mechanisms of Action and Pharmacologic Effects

  48. Chapter 42: Clinical Pharmacology of Other Drugs Used as Hypnotics

  49. Chapter 43: Wake-Promoting Medications: Basic Mechanisms and Pharmacology

  50. Chapter 44: Wake-Promoting Medications: Efficacy and Adverse Effects

  51. Chapter 45: Drugs That Disturb Sleep and Wakefulness

  52. Chapter 46: Effects of Hypnotic Drugs on Driving Performance

  53. Section 7: Psychobiology and Dreaming

  54. Chapter 47: Introduction

  55. Chapter 48: Why We Dream

  56. Chapter 49: Dream Content: Quantitative Findings

  57. Chapter 50: Brain Correlates of Sucessful Dream Recall

  58. Chapter 51: Neurobiology of Dreaming

  59. Chapter 52: Lucid Dreaming

  60. Chapter 53: Nightmares and Nightmare Function

  61. Chapter 54: Incorporation of waking Experiences into Dreams

  62. Chapter 55: Dreams and Nightmares in Posttraumatic Stress Disorder

  63. Chapter 56: Emotion, Motivation, and Reward in Relation to Dreaming

  64. Section 8: Impact, Presentation, and Diagnosis

  65. Chapter 57: Approach to the Patient with Disordered Sleep

  66. Chapter 58: Cardinal Manifestations of Sleep Disorders

  67. Chapter 59: Physical Examination in Sleep Medicine

  68. Chapter 60: Use of Clinical Tools and Tests in Sleep Medicine

  69. Chapter 61: Classification of Sleep Disorders

  70. Chapter 62: Epidemiology of Sleep Medicine

  71. Chapter 63: Sleep Medicine, Public Policy, and Public Health

  72. Chapter 64: Sleep and Athletic Performance

  73. Section 9: Legal Topics in Sleep Medicine

  74. Chapter 65: Sleep Forensics: Criminal Culpability for Sleep-Related Violence

  75. Chapter 66: Legal Obligations of Persons Who Have Sleep Disorders or Who Treat or Hire Them

  76. Chapter 67: Legal Aspects of Fatigue-and Safety-Sensitive Professions

  77. Chapter 68: Sleep Medicine Clinical Practice and Compliance – United States

  78. Chapter 69: Sleep Medicine Clinical Practice and Compliance – Europe

  79. Section 10: Occupational Sleep Medicine

  80. Chapter 70: Introduction

  81. Chapter 71: Performance Deficits During Sleep Loss and Their Operational Consequences

  82. Chapter 72: Sleep and Performance Prediction Modeling

  83. Chapter 73: Fatigue Risk Management Systems

  84. Chapter 74: Drowsiness in Transportation Workers

  85. Chapter 75: Shift Work, Shift-Work Disorder, and Jet Lag

  86. Chapter 76: Sleep Problems in First Responders and in Deployed Military Personnel

  87. Chapter 77: Sleep, Occupational stress, and Burnout

  88. Chapter 78: Optimizing Shift Scheduling

  89. Chapter 79: Obstructive Sleep Apnea in the Workplace

  90. Section 11: Insonmnia

  91. Chapter 80: Insomnia: Recent Developments and Future Directions

  92. Chapter 81: Insomnia: Epidemiology and Risk Factors

  93. Chapter 82: Etiology and Pathophysiology of Insomnia

  94. Chapter 83: Insomnia Diagnosis Assessment, and Evaluation

  95. Chapter 84: Insomnia and Health

  96. Chapter 85: Cognitive Behavioral Therapies for Insomnia I: Approaches and Efficacy

  97. Chapter 86: Psychological and Behavioral Treatments for Insomnia II: Implementation and Specific Population

  98. Chapter 87: Pharmacologic Treatment of Insomnia: Benzodiazepine Receptor Agonists

  99. Chapter 88: Pharmacologic Treatment of Insomnia: Other Medication

  100. Section 12: Neurological Disorders

  101. Chapter 89: Narcolepsy: Genetic, Immunology, and Pathophysiology

  102. Chapter 90: Narcolepsy: Diagnosis and Management

  103. Chapter 91: Idiopathic Hypersomnia

  104. Chapter 92: Parkinsonism

  105. Chapter 93: Sleep and Stroke

  106. Chapter 94: Sleep and Neuromuscular Diseases

  107. Chapter 95: Restless Legs Syndrome and Periodic Limb Movements During Sleep

  108. Chapter 96: Alzheimer's Disease and Other Dementias

  109. Chapter 97: Epilepsy, Sleep, and Sleep Disorders

  110. Chapter 98: Other Neurological Disorders

  111. Chapter 99: Sleep Disorders after Traumatic Brain Injury

  112. Chapter 100: Kleine-Levin Syndrome

  113. Section 13: Parasomnias

  114. Chapter 101: Parasomnias: Overview and Approach

  115. Chapter 102: Non-Rapid Eye Movement Parasomnias: Clinical Spectrum, Diagnostic Features, and Management

  116. Chapter 103: Rapid Eye Movement Sleep Parasomnias

  117. Chapter 104: Nightmares and Dream Disturbances

  118. Chapter 105: Other Parasomnias

  119. Chapter 106: Sleep-Related Movement Disorders and Their Unique Motor Manifestations

  120. Section 14: Sleep Breathing Disorders

  121. Chapter 107: Sleep Related Breathing Disorders: Classification

  122. Chapter 108: Sleep Breathing Disorders: Clinical Overview

  123. Chapter 109: Central Sleep Apnea: Definitions, and Pathophysiology, Genetics, and Epidemiology

  124. Chapter 110: Central Sleep Apnea: Diagnosis and Management

  125. Chapter 111: Anatomy and Physiology of Upper Airway Obstruction

  126. Chapter 112: Snoring and Pathologic Upper Airway Resistance Syndromes

  127. Chapter 113: Obstructive Sleep Apnea: Phenotypes and Genetics

  128. Chapter 114: Obstructive Sleep Apnea: Clinical Features, Evaluation, and Principles of Management

  129. Chapter 115: Positive Airway Pressure Treatment for Obstructive Sleep Apnea

  130. Chapter 116: Medical and Device Treatment for Obstructive Sleep Apnea: Alternative, Adjunctive, and Complementary Therapies

  131. Chapter 117: Obstructive Sleep Apnea and the Central Nervous System: Neural Adaptive Processes, Cognition and Performance

  132. Chapter 118: Obstructive Sleep Apnea and Metabolic Disorders

  133. Chapter 119: Overlap Syndromes of Sleep and Breathing Disorders

  134. Chapter 120: Obesity Hypoventilation Syndrome

  135. Chapter 121: Obstructive Sleep Apnea, Obesity, and Bariatric Surgery

  136. Chapter 122: Sleep and Breathing at High Altitude

  137. Section 15: Cardiovascular Disorders

  138. Chapter 123: Sleep and Cardiovascular Disease: Present and Future

  139. Chapter 124: Sleep-Related Cardiac Risk

  140. Chapter 125: Cardiac Arrythmogenesis during Sleep: Mechanisms, Diagnosis, and Therapy

  141. Chapter 126: Cardiovascular Effects of Sleep-Related Breathing Disorders

  142. Chapter 127: Systemic and Pulmonary Hypertension in Obstructive Sleep Apnea

  143. Chapter 128: Coronary Artery Disease and Obstructive Sleep Apnea

  144. Chapter 129: Heart Failure

  145. Section 16: Other Medical Disorders

  146. Chapter 130: Sleep and Fatigue in Cancer Patients

  147. Chapter 131: Fibromyalgia and Chronic Fatigue Syndromes

  148. Chapter 132: Endocrine Disorders

  149. Chapter 133: Pain and Sleep

  150. Chapter 134: Sleep and Chronic Kidney Disease

  151. Chapter 135: Sleep in Critically Ill Patients

  152. Section 17: Psychiatric Disorders

  153. Chapter 136: Anxiety Disorders and Posttraumatic Stress Disorder

  154. Chapter 137: Unipolar Major Depression

  155. Chapter 138: Bipolar Disorder

  156. Chapter 139: Schizophrenia

  157. Chapter 140: Medication and Substance Abuse

  158. Chapter 141: Sleep Disturbances in Attention-Deficit/Hyperactivity Disorder

  159. Section 18: Dentistry and Otolaryngology in Sleep Medicine

  160. Chapter 142: Role of Dentistry and Otolaryngology in Sleep Medicine

  161. Chapter 143: Orophayngeal Growth & Skeletal Malformations

  162. Chapter 144: Sleep Bruxism: Definition, Prevalence, Classification, Etiology, and Consequences

  163. Chapter 145: Sleep Bruxism: Diagnostic Considerations

  164. Chapter 146: Orofacial Pain and Temporomandibular Disorders in Relation to Sleep-Disordered Breathing and Sleep Bruxism

  165. Chapter 147: Oral Appliances for the Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome and for Concomitant Sleep Bruxism

  166. Chapter 148: Anesthesia in Upper Airway Surgery for Obstructive Sleep Apnea

  167. Chapter 149: Upper Airway Surgery to Treat Obstructive sleep-Disordered Breathing

  168. Chapter 150: Pharmacotherapy, Complementary, Alternative Medicine for Sleep Bruxism

  169. Section 19: Sleep in Older Adults

  170. Chapter 151: Psychiatric and Medical Comorbidities, and Effects of Medications in Older Adults

  171. Chapter 152: Obstructive Sleep Apnea in Older Adults

  172. Chapter 153: Insomnia in Older Adults

  173. Chapter 154: Circadian Rhythms in Older Adults

  174. Section 20: Sleep in Women

  175. Chapter 155: Sex Differences and Menstrual-Related Changes in Sleep and Circadian Rhythms

  176. Chapter 156: Sleep and Sleep Disorders Associated with Pregnancy

  177. Chapter 157: Sleep-Disordered Breathing in Pregnancy

  178. Chapter 158: Postpartum Period and Early Motherhood

  179. Chapter 159: Sleep and Menopause

  180. Section 21: Instrumentation and Methodology

  181. Chapter 160: Polysomnography and Beyond

  182. Chapter 161: Sleep Stage Scoring

  183. Chapter 162: Central Nervous System Arousals & Cyclic Alternating Patterns

  184. Chapter 163: Neurologic Monitoring Techniques

  185. Chapter 164: Monitoring Techniques for Evaluating Suspected Sleep-Related Breathing Disorders

  186. Chapter 165: Home Sleep Testing

  187. Chapter 166: Cardiopulmonary Coupling Sleep Spectrograms

  188. Chapter 167: Pulse Wave Analysis During Sleep

  189. Chapter 168: Recording and Scoring Sleep-Related Movements

  190. Chapter 169: Evaluating Sleepiness

  191. Chapter 170: Chronobiologic Monitoring Techniques

  192. Chapter 171: Actigraphy

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