Statistical Issues in Drug Development

Statistical Issues in Drug Development, 3rd Edition, is a reference that examines the application of statistics to pharmaceutical research. The volume clarifies foundational statistical challenges in drug development while encouraging communication between statisticians and life scientists.

Coverage introduces the role played by statistics in development programs and analyzes topics through four perspectives: historical, methodological, technical, and professional. It also reviews controversial subjects such as treatment allocation in clinical trials, baselines and covariate information, and treatment effect measurement.

Designed for life scientists and drug development professionals, this guide delivers an accessible discussion of complex concepts while directly addressing significant disagreements within the discipline of statistics.