Statistical Methods in Diagnostic Medicine

Statistical Methods in Diagnostic Medicine, 3rd Edition, is an academic textbook that presents statistical methodologies for evaluating diagnostic tests in clinical practice. The work provides formal analytical approaches to evaluate test performance, analyze diagnostic data, and address methodological questions across varied medical study designs.

This third edition introduces three new chapters that focus on risk prediction, quantitative imaging biomarkers, and test efficacy and effectiveness. The content expands previous discussions on biomarker evaluation and benefit-risk assessment. It further delivers updated technical guidance for sample size calculations, accuracy estimation methods, and comparative analysis for competing diagnostic tests.

The volume is designed for biostatisticians, applied statisticians, clinical researchers, regulatory professionals, and graduate students in quantitative fields. Published by Wiley-Blackwell with print ISBN 9781394220212 and eText ISBN 9781394220229, the textbook offers structured material to support advanced graduate coursework and specialized research practice.