Systems Biology

Systems Biology, 1st Edition, surveys experimental and computational methods applied to investigate biological systems across multiple branches of the discipline. Part of the Advances Biotechnology series, the volume connects quantitative modeling with laboratory research applications.

Coverage includes strategies for the integrative analysis of omics data alongside techniques that quantify metabolic fluxes using 13C-labelled substrates. The book also explains genome-scale metabolic modeling, illustrating concepts through human metabolism and the model organism Escherichia coli.

The text highlights applications in cell factory engineering and human health, emphasizing regulatory networks and processes such as cellular ageing and organogenesis. Discussions also address genome editing methodologies that allow targeted genetic modifications and dynamic gene expression control.