
The Lung
Development, Aging and the Environment
by Kent E. Pinkerton, Richard Harding, Elizabeth Georgian
3rd Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780323918244 |
| eText ISBN | 9780323915700 |
| Publisher | Academic Press |
| Publishing Year | 2024 |
| Edition | 3rd Edition |
| Language | English |
| Pages | 680 |
The reference volume The Lung: Development, Aging and the Environment, 3rd Edition, edited by Kent E. Pinkerton, Richard Harding, and Elizabeth Georgian, presents an extensive biological analysis of respiratory structure and function across human life stages. The text details normal lung growth, pediatric respiratory risks, environmental contaminant impacts, and genetic factors in lung disease susceptibility.
The volume synthesizes complex physiological mechanisms into thematic research areas. Chapters trace lung progenitor cell specification, alveolar and vascular development, the pulmonary surfactant system in health and prematurity, adaptation to mechanical signals, and the ontogeny of the pulmonary immune system, leading into structural changes during normal lung aging.
Updated content emphasizes emerging environmental exposures, detailing the impact of prenatal exposure to wildfires alongside nicotine and E-cigarette vaping during early development. This reference supports pulmonologists, physicians, and basic scientists analyzing structural respiratory alterations and environmental susceptibility.
Table of Contents
Chapter 1: Lung Progenitor Cell Specification and Morphogenesis
Chapter 2: Alveolar Development
Chapter 3: Development of the Innervation of the Lower Airways: Structure and Function
Chapter 4: Pulmonary Vascular Development
Chapter 5: Developmental Physiology of the Pulmonary Circulation
Chapter 6: Physical, Endocrine, and Growth Factors in Lung Development
Chapter 7: The Development and FUnction of the Pulmonary Surfactant System in Health, Prematurity, and Genetic Disease
Chapter 8: Ontogeny of the Pulmonary Immune System
Chapter 9: Macrophages and the Lung
Chapter 10: Adaptation to Mechanical Signals in the Lung: Recruitment of Reserves, Remodeling, and Regrowth
Chapter 11: Pulmonary Transition at Birth
Chapter 12: Normal Aging of the Lung
Chapter 13: Epigenetics and the Developmental Origins of Lung Disease
Chapter 14: Pulmonary Consequences of Preterm Birth
Chapter 15: Preterm Birth and the Developing Lung: Programming Effects on Lung Structure and Function
Chapter 16: The Effects of Neonatal Hyperoxia on Lung Development
Chapter 17: Restricted Growth During Early Development: Effects on Lung Structure and Lung Function
Chapter 18: Cell-Based Strategies for the Treatment of Injury to the Developing Lung
Chapter 19: Effects of Environmental Tobacco Smoke during Early Life Stages
Chapter 20: Nicotine Exposure during Early Development: Effects on the Lung
Chapter 21: Implications of Early Life Exposures to Electronic Nicotine Delivery System (ENDS) Aerosols
Chapter 22: In Utero Exposure to Allergens and Development of the Allergic Phenotype in the Neonate
Chapter 23: Effect of Environment on the Developing and Adult Pulmonary Surfactant System and in the Aging Lung
Chapter 24: Environmental Determinants of Lung Aging
Chapter 25: The Role of Epigenetics in Lung Diseases and Environmental Exposures
Chapter 26: The Dynamic Microbiotal Changes in the Human: Impact on the Developing Lung
Chapter 27: Viral Respiratory Pathogens and Lung Injury in Pregnancy, with Focus on Epidemiology and Pathophysiology of ARDS amidst the COVID-19 Pandemic
Chapter 28: The Lung Exposome: Accelerating Precision Respiratory Health
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