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The Lung cover

The Lung

Development, Aging and the Environment

by Kent E. Pinkerton, Richard Harding, Elizabeth Georgian

3rd Edition

Publisher: Academic Press

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Book Details

Print ISBN9780323918244
eText ISBN9780323915700
PublisherAcademic Press
Publishing Year2024
Edition3rd Edition
LanguageEnglish
Pages680

The reference volume The Lung: Development, Aging and the Environment, 3rd Edition, edited by Kent E. Pinkerton, Richard Harding, and Elizabeth Georgian, presents an extensive biological analysis of respiratory structure and function across human life stages. The text details normal lung growth, pediatric respiratory risks, environmental contaminant impacts, and genetic factors in lung disease susceptibility.

The volume synthesizes complex physiological mechanisms into thematic research areas. Chapters trace lung progenitor cell specification, alveolar and vascular development, the pulmonary surfactant system in health and prematurity, adaptation to mechanical signals, and the ontogeny of the pulmonary immune system, leading into structural changes during normal lung aging.

Updated content emphasizes emerging environmental exposures, detailing the impact of prenatal exposure to wildfires alongside nicotine and E-cigarette vaping during early development. This reference supports pulmonologists, physicians, and basic scientists analyzing structural respiratory alterations and environmental susceptibility.

Table of Contents

  1. Chapter 1: Lung Progenitor Cell Specification and Morphogenesis

  2. Chapter 2: Alveolar Development

  3. Chapter 3: Development of the Innervation of the Lower Airways: Structure and Function

  4. Chapter 4: Pulmonary Vascular Development

  5. Chapter 5: Developmental Physiology of the Pulmonary Circulation

  6. Chapter 6: Physical, Endocrine, and Growth Factors in Lung Development

  7. Chapter 7: The Development and FUnction of the Pulmonary Surfactant System in Health, Prematurity, and Genetic Disease

  8. Chapter 8: Ontogeny of the Pulmonary Immune System

  9. Chapter 9: Macrophages and the Lung

  10. Chapter 10: Adaptation to Mechanical Signals in the Lung: Recruitment of Reserves, Remodeling, and Regrowth

  11. Chapter 11: Pulmonary Transition at Birth

  12. Chapter 12: Normal Aging of the Lung

  13. Chapter 13: Epigenetics and the Developmental Origins of Lung Disease

  14. Chapter 14: Pulmonary Consequences of Preterm Birth

  15. Chapter 15: Preterm Birth and the Developing Lung: Programming Effects on Lung Structure and Function

  16. Chapter 16: The Effects of Neonatal Hyperoxia on Lung Development

  17. Chapter 17: Restricted Growth During Early Development: Effects on Lung Structure and Lung Function

  18. Chapter 18: Cell-Based Strategies for the Treatment of Injury to the Developing Lung

  19. Chapter 19: Effects of Environmental Tobacco Smoke during Early Life Stages

  20. Chapter 20: Nicotine Exposure during Early Development: Effects on the Lung

  21. Chapter 21: Implications of Early Life Exposures to Electronic Nicotine Delivery System (ENDS) Aerosols

  22. Chapter 22: In Utero Exposure to Allergens and Development of the Allergic Phenotype in the Neonate

  23. Chapter 23: Effect of Environment on the Developing and Adult Pulmonary Surfactant System and in the Aging Lung

  24. Chapter 24: Environmental Determinants of Lung Aging

  25. Chapter 25: The Role of Epigenetics in Lung Diseases and Environmental Exposures

  26. Chapter 26: The Dynamic Microbiotal Changes in the Human: Impact on the Developing Lung

  27. Chapter 27: Viral Respiratory Pathogens and Lung Injury in Pregnancy, with Focus on Epidemiology and Pathophysiology of ARDS amidst the COVID-19 Pandemic

  28. Chapter 28: The Lung Exposome: Accelerating Precision Respiratory Health

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▶Research Sources (15)
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  • The Lung: Development, Aging and the Environment - Google Books
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  • The Lung - Edison State Community College Online Bookstore