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The Molecular Neurobiology of Depression cover

The Molecular Neurobiology of Depression

by Subir Ranjan Kundu, Jaya Sarkar

1st Edition

Publisher: Academic Press

(0 reviews)
Neuroscience

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Book Details

Print ISBN9780443331121
eText ISBN9780443331138
PublisherAcademic Press
Publishing Year2025
Edition1st Edition
LanguageEnglish

The Molecular Neurobiology of Depression, 1st Edition, provides a specialized reference on the genetic, physiological, and molecular factors tied to depressive conditions and suicidal behavior. Written for researchers and graduate students, this reference work integrates neuropsychiatry with molecular neurobiology to clarify how biological pathways influence psychiatric vulnerability.

Main coverage centers on candidate gene studies, evaluating monoamine oxidase single-nucleotide polymorphisms alongside serotoninergic and dopaminergic gene variations. The volume also investigates how Corticotropin-Releasing Factor modulates stress responses through the regulation of the hypothalamic-pituitary-adrenal axis, establishing direct links between endocrine system regulation and psychiatric conditions.

By incorporating case studies alongside an interdisciplinary perspective, the text explores neurobiological evolution research in relation to suicide biology. It evaluates structural and functional features of DNA, including non-coding DNA, to identify potential genetic triggers of depressive disorders. This reference provides graduate students and academic researchers with a grounded resource on the biological drivers of suicidal behavior.

Table of Contents

  1. Chapter 1: Humans: The Social Animals in Anthropocene, Craving Oblivion through Suicide

  2. Chapter 2: In quest of Exploring the Heritability of Suicidal Behavior Permeates through Familial Aggregation

  3. Chapter 3: Candidate Gene Studies of Mental Health Disorder and Suicidal Behavior-1: Concerning Monoamino Oxidases (Single-Nucleotide) Polymorphisms

  4. Chapter 4: Candidate Gene Studies of Mental Health Disorder and Suicidal Behavior-2: In Relation to Serotoninergic Polymorphisms

  5. Chapter 5: Candidate Gene Studies of Mental Health Disorder and Suicidal Behavior-3: In Relation to Dopaminergic Polymorphisms

  6. Chapter 6: Candidate Gene Studies of Mental Health Disorder and Suicidal Behavior-4: Potential role of CRF (Corticotropin-Releasing Factor) in stress response by regulating the mode of action of HPA Axis

  7. Chapter 7: Neurobiological Frontiers in Suicidal Behavior: In Relation to Immune Systems and Blood Hormones-I

  8. Chapter 8: Neurobiological Frontiers in Suicidal Behavior in Females: Concerning Immune Systems and Blood Hormones

  9. Chapter 9: Neurobiological Frontiers in Suicidal Behavior in Males: Concerning Immune Systems and Blood Hormones

  10. Chapter 10: Neurobiological Footprints of Suicidal Behavior: Potential Role of Proteomics and Gene Actions

  11. Chapter 11: Neurobiological Footprints of Suicidal Behavior: In association with Rare variant genetic architecture, gene pathways and functional genomics

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  • New Insight Into the Biology of Depression

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