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Antibiotic Resistance and Nanotherapy cover

Antibiotic Resistance and Nanotherapy

by Awanish Kumar, Sharda Bharti

1st Edition

Publisher: Academic Press

(0 reviews)
MicrobiologyPharmacology

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Book Details

Print ISBN9780443363887
eText ISBN9780443363894
PublisherAcademic Press
Publishing Year2026
Edition1st Edition
LanguageEnglish
Pages482

The 1st Edition of Antibiotic Resistance and Nanotherapy, edited by Awanish Kumar and Sharda Bharti and published by Academic Press in 2026, investigates targeted nanoparticle applications designed to eliminate resistant bacterial pathogens. This reference volume provides researchers, academics, and graduate students across microbiology, biotechnology, and biomedical sciences with an organized conceptual framework for evaluating nanoscale therapeutic interventions against resistant infection profiles.

The text structures its scientific analysis by categorizing drug resistance mechanisms according to biological location, distinguishing between intracellular and extracellular pathogens. It systematically examines engineered delivery platforms, detailing how metal-based, lipid-based, and polymer-based nanomedicines can be deployed against specific microbial targets to overcome established resistance pathways in diverse cellular environments.

In addition, the content addresses biofilm-mediated bacterial resistance by explaining how specialized nanoparticle interventions disrupt c-di-GMP molecular signaling along with quorum-sensing communication pathways. This thematic focus helps academic readers analyze how custom nanotherapeutic vectors dismantle protective bacterial matrices and interrupt critical intercellular signaling networks in microbial communities.

Table of Contents

  1. Chapter 1: Introduction to planktonic and biofilm-mediated antimicrobial resistance and role of nanotechnology in overcoming biofilm-mediated antibiotic resistance

  2. Chapter 2: Key determinants of antimicrobial resistance: exploring the influence of antibiotic pollution on the emergence of multidrug-resistant microbes

  3. Chapter 3: Drug resistance mechanism in intracellular pathogens and modulation

  4. Chapter 4: Metal-based nanomedicine against intracellular pathogens

  5. Chapter 5: Lipid-based nanomedicine against intracellular pathogens

  6. Chapter 6: Metal-based nanomedicine against extracellular pathogens

  7. Chapter 7: Polymer-based nanomedicine against extracellular pathogens

  8. Chapter 8: Lipid-based nanomedicine against extracellular pathogens

  9. Chapter 9: Interaction between infected host cells and nanodelivery systems

  10. Chapter 10: Innovative strategies utilizing nanoparticles to disrupt c-di-GMP and quorum-sensing signaling pathways to combat antibiotic resistance induced by biofilms

  11. Chapter 11: CRISPR-Cas systems for antibiotic resistance

  12. Chapter 12: Synergistic effects of natural compounds and repurposed drugs in nanotherapy: a strategy to combat biofilm-associated infections

  13. Chapter 13: Safety, ethical, regulatory issues, and challenges of nanotherapy for antimicrobial resistance

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