
Antibiotic Resistance and Nanotherapy
by Awanish Kumar, Sharda Bharti
1st Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780443363887 |
| eText ISBN | 9780443363894 |
| Publisher | Academic Press |
| Publishing Year | 2026 |
| Edition | 1st Edition |
| Language | English |
| Pages | 482 |
The 1st Edition of Antibiotic Resistance and Nanotherapy, edited by Awanish Kumar and Sharda Bharti and published by Academic Press in 2026, investigates targeted nanoparticle applications designed to eliminate resistant bacterial pathogens. This reference volume provides researchers, academics, and graduate students across microbiology, biotechnology, and biomedical sciences with an organized conceptual framework for evaluating nanoscale therapeutic interventions against resistant infection profiles.
The text structures its scientific analysis by categorizing drug resistance mechanisms according to biological location, distinguishing between intracellular and extracellular pathogens. It systematically examines engineered delivery platforms, detailing how metal-based, lipid-based, and polymer-based nanomedicines can be deployed against specific microbial targets to overcome established resistance pathways in diverse cellular environments.
In addition, the content addresses biofilm-mediated bacterial resistance by explaining how specialized nanoparticle interventions disrupt c-di-GMP molecular signaling along with quorum-sensing communication pathways. This thematic focus helps academic readers analyze how custom nanotherapeutic vectors dismantle protective bacterial matrices and interrupt critical intercellular signaling networks in microbial communities.
Table of Contents
Chapter 1: Introduction to planktonic and biofilm-mediated antimicrobial resistance and role of nanotechnology in overcoming biofilm-mediated antibiotic resistance
Chapter 2: Key determinants of antimicrobial resistance: exploring the influence of antibiotic pollution on the emergence of multidrug-resistant microbes
Chapter 3: Drug resistance mechanism in intracellular pathogens and modulation
Chapter 4: Metal-based nanomedicine against intracellular pathogens
Chapter 5: Lipid-based nanomedicine against intracellular pathogens
Chapter 6: Metal-based nanomedicine against extracellular pathogens
Chapter 7: Polymer-based nanomedicine against extracellular pathogens
Chapter 8: Lipid-based nanomedicine against extracellular pathogens
Chapter 9: Interaction between infected host cells and nanodelivery systems
Chapter 10: Innovative strategies utilizing nanoparticles to disrupt c-di-GMP and quorum-sensing signaling pathways to combat antibiotic resistance induced by biofilms
Chapter 11: CRISPR-Cas systems for antibiotic resistance
Chapter 12: Synergistic effects of natural compounds and repurposed drugs in nanotherapy: a strategy to combat biofilm-associated infections
Chapter 13: Safety, ethical, regulatory issues, and challenges of nanotherapy for antimicrobial resistance
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