Biophysics

Mark C. Leake authors Biophysics: Tools and Techniques for the Physics of Life, 2nd Edition, an undergraduate textbook that introduces physical science students to biological systems and quantitative biophysical methodologies. The volume delivers essential biological concepts for physical scientists alongside physical science toolboxes used to analyze biological matter.

The core chapters detail foundational optical detection and imaging techniques across ultraviolet, visible, and infrared spectra, progressing into frontier spectroscopy and microscopy. Nonoptical wave detection methods are systematically examined, incorporating radio waves, microwaves, X-rays, gamma radiation, and high-energy particle techniques. Additional thematic coverage includes single-molecule tools, live-cell and test-tube methods, and specialized procedures designed to measure or manipulate biological forces during quantitative experiments.

Integrated worked examples and step-by-step solved exercises assist students in applying physical principles to practical biophysical calculations. These structured pedagogical features prepare undergraduate physical science students and future multidisciplinary researchers for upper-level coursework across biological physics.