Biophysics of Tissue Self-Organization in Morphogenesis
The Role of Dynamics Along the Biointerface
by Ivana Pajic-Lijakovic
1st Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780443300486 |
| eText ISBN | 9780443300493 |
| Publisher | Academic Press |
| Publishing Year | 2026 |
| Edition | 1st Edition |
| Language | English |
| Pages | 334 |
Biophysics of Tissue Self-Organization in Morphogenesis, 1st Edition, investigates physical and biological dynamics along biointerfaces to explain structural formation in living systems. Author Ivana Pajic-Lijakovic details specific biological mechanisms that drive cell self-rearrangement across multiple spatial scales, ranging from subcellular components up to supracellular tissue structures.
The volume details interactions between tissue structures and the surrounding extracellular matrix, establishing how mechanical dynamics shape biological boundaries. It explores these self-organizing behaviors in both in vivo settings and in vitro organoid systems. In addition, the text applies established engineering principles to formulate approaches for solving complex biological and medical problems.
Spanning 334 pages, this edition provides clear analytical foundations for advanced academic inquiry in physical biology. The text offers reference value for established researchers in cell biology, tissue biomechanics, and biophysics who analyze dynamic physical properties and structural organization within developing biological tissues.
Table of Contents
Chapter 1: Cell adhesion: Common mechanisms and physical principles
Chapter 2: Analysis of the effect of cell movement on gene expression dynamics in development
Chapter 3: Force transmission across scales: Examples and measuring methods
Chapter 4: The impact of air pollution on the tissue self-organisation within co[1]cultured lung systems
Chapter 5: How physical cues guide cell collectives, from local adhesion to global force transmission
Chapter 6: Cellular death and division events at tissue interfaces: A chicken-or[1]the-egg situation
Chapter 7: Active Nematics: Exploring the Interplay between structure and dynamics in cell cultures
Chapter 8: The dynamics along the epithelial-cancer bio-interface within co[1]cultured cell spheroids: Physical aspects
Chapter 9: Dynamical interplay at the interfaces of cancer cells, immune cells and stromal cells in the extracellular space of artificial model systems and tissues
Chapter 10: Techniques development to quantify cell-scale dynamic mechanical interactions in extracellular matrices of tissues
Chapter 11: Mathematical modelling approaches to collective cell movement: Leader vs. follower cells
Chapter 12: Engineering of human tissues
Chapter 13: Conclusion and outlook
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