Comprehensive Clinical Nephrology
by Richard J. Johnson, Jurgen Floege, Marcello Tonelli
7th Edition
Publisher: Elsevier
Book Details
| Print ISBN | 9780323825924 |
| eText ISBN | 9780323825948 |
| Publisher | Elsevier |
| Publishing Year | 2023 |
| Edition | 7th Edition |
| Language | English |
| Pages | 1328 |
Comprehensive Clinical Nephrology, 7th Edition, offers a thorough medical textbook geared toward nephrology fellows, clinical practitioners, and hospital internists who care for individuals with kidney disease. The work provides practical, evidence-grounded direction for evaluating, diagnosing, and managing a wide range of acute and chronic renal conditions.
The content addresses key clinical topics, starting with fluid and electrolyte disorders, acute kidney injury, and systemic hypertension. Broad thematic coverage extends across complex presentations of glomerular disease, diabetic kidney disease, and progressive renal failure, concluding with clinical protocols for maintenance dialysis modalities and renal transplantation.
To clarify complex diagnostic and pathological concepts, the text incorporates more than 1,500 full-color figures detailing disease mechanisms and key anatomical findings. The volume was named an Essential Purchase in Nephrology within the 2026 Doody's Core Titles, confirming its established role in subspecialty fellowship training and medical practice.
Table of Contents
Chapter 1: Renal Anatomy
Chapter 2: Renal Physiology
Chapter 3: Assessment of Glomerular Filtration Rate
Chapter 4: Urinalysis
Chapter 5: Point of Care Ultrasound in Nephrology
Chapter 6: Radiologic and Nuclear Imaging in Nephrology
Chapter 7: Kidney Biopsy
Chapter 8: Disorders of Extracellular Volume
Chapter 9: Disorders of Water Metabolism
Chapter 10: Disorders of Potassium Metabolism
Chapter 11: Disorders of Calcium, Phosphate, and Magnesium Metabolism
Chapter 12: Normal Acid-Base Balance
Chapter 13: Metabolic Acidosis
Chapter 14: Metabolic Alkalosis
Chapter 15: Respiratory Acidosis, Respiratory Alkalosis, and Mixed Acid-Base Disorders
Chapter 16: Introduction to Glomerular Disease: Clinical Presentations
Chapter 17: Introduction to Glomerular Disease: Histologic Classification and Pathogenesis
Chapter 18: Minimal Change Disease
Chapter 19: Primary and Secondary (Nongenetic) Causes of Focal and Segmental Glomerulosclerosis
Chapter 20: Inherited Causes of Nephrotic Syndrome
Chapter 21: Membranous Nephropathy
Chapter 22: Immunoglobulin-Mediated Glomerulonephritis With a Membranoproliferative Pattern of Injury and Cryoglobulinemic Glomerulonephritis
Chapter 23: Glomerulonephritis Associated With Complement Disorders
Chapter 24: Immunoglobulin A Nephropathy and Immunoglobulin A Vasculitis (Henoch-Schönlein Purpura)
Chapter 25: Anti–Glomerular Basement Membrane Disease and Goodpasture Disease
Chapter 26: Renal and Systemic Vasculitis
Chapter 27: Lupus Nephritis
Chapter 28: Monoclonal Immunoglobulin–Related Glomerular Diseases and Renal Amyloidosis
Chapter 29: Rare Glomerular Disorders
Chapter 30: Thrombotic Microangiopathies, Including Hemolytic Uremic Syndrome
Chapter 31: Pathogenesis, Clinical Manifestations, and Natural History of Diabetic Kidney Disease
Chapter 32: Prevention and Treatment of Diabetic Kidney Disease
Chapter 33: Management of Patients With Diabetes and Chronic Kidney Disease
Chapter 34: Normal Blood Pressure Control and the Evaluation of Hypertension
Chapter 35: Primary Hypertension
Chapter 36: Nonpharmacologic Prevention and Treatment of Hypertension
Chapter 37: Pharmacologic Treatment of Hypertension
Chapter 38: Evaluation and Treatment of Hypertensive Urgencies and Emergencies
Chapter 39: Endocrine Causes of Hypertension: Aldosterone
Chapter 40: Other Endocrine Causes of Hypertension
Chapter 41: Neurogenic Hypertension, Including Hypertension Associated With Stroke or Spinal Cord Injury
Chapter 42: Blood Pressure Management in the Dialysis Patient
Chapter 43: Renovascular Hypertension, Atherosclerotic Renal Vascular Disease, and Thromboembolic Kidney Disease
Chapter 44: Kidney Physiology and Complications in Normal Pregnancy
Chapter 45: Pregnancy With Preexisting Kidney Disease
Chapter 46: Autosomal Dominant Polycystic Kidney Disease
Chapter 47: Other Cystic Kidney Diseases
Chapter 48: Alport Syndrome and Other Familial Glomerular Syndromes
Chapter 49: Inherited Disorders of Sodium and Water Handling
Chapter 50: Fanconi Syndrome and Other Proximal Tubule Disorders
Chapter 51: Sickle Cell Diseases and the Kidney
Chapter 52: Congenital Anomalies of the Kidney and Urinary Tract
Chapter 53: Urinary Tract Infections in Adults
Chapter 54: Tuberculosis of the Urinary Tract
Chapter 55: Fungal Infections of the Urinary Tract
Chapter 56: The Kidney in Schistosomiasis
Chapter 57: Glomerular Diseases Associated With Infection
Chapter 58: Human Immunodeficiency Virus Infection and the Kidney
Chapter 59: Kidney Diseases Associated With Coronaviruses
Chapter 60: Nephrolithiasis and Nephrocalcinosis
Chapter 61: Urinary Tract Obstruction
Chapter 62: Primary Vesicoureteral Reflux and Reflux Nephropathy
Chapter 63: Urologic Issues for the Nephrologist
Chapter 64: Acute Interstitial Nephritis
Chapter 65: Chronic Interstitial Nephritis
Chapter 66: Endemic Nephropathies
Chapter 67: Oncology: Kidney Disease in Cancer Patients
Chapter 68: Myeloma and the Kidney
Chapter 69: Kidney Disease in Liver, Cardiac, Lung, and Hematopoietic Stem Cell Transplantation
Chapter 70: Pathophysiology and Etiology of Acute Kidney Injury
Chapter 71: Acute Kidney Injury in the Tropics
Chapter 72: Diagnosis and Clinical Evaluation of Acute Kidney Injury
Chapter 73: Epidemiology and Prognostic Impact of Acute Kidney Injury and Acute Kidney Disease
Chapter 74: Prevention and Nondialytic Management of Acute Kidney Injury
Chapter 75: Extracorporeal Therapies for Acute Kidney Injury and Heart Failure
Chapter 76: Hepatorenal Syndrome
Chapter 77: Principles of Drug Therapy, Dosing, and Prescribing in Chronic Kidney Disease and Kidney Replacement Therapy
Chapter 78: Common Issues in Prescribing in Kidney Disease and Kidney Replacement Therapy
Chapter 79: Herbal and Over-the-Counter Medicines and the Kidney
Chapter 80: Epidemiology of Chronic Kidney Disease and Dialysis
Chapter 81: Pathophysiology of Disease Progression in Proteinuric and Nonproteinuric Kidney Disease
Chapter 82: Slowing the Progression of Kidney Disease
Chapter 83: Clinical Evaluation and Management of Chronic Kidney Disease
Chapter 84: Pathogenesis and Risk of Cardiovascular Disease in Chronic Kidney Disease
Chapter 85: Practical Management of Cardiovascular Disease in Chronic Kidney Disease
Chapter 86: Anemia in Chronic Kidney Disease
Chapter 87: Other Blood and Immune Disorders in Chronic Kidney Disease
Chapter 88: Bone and Mineral Disorders in Chronic Kidney Disease
Chapter 89: Neurologic Complications of Chronic Kidney Disease
Chapter 90: Nutrition in Chronic Kidney Disease
Chapter 91: Dermatologic Manifestations of Chronic Kidney Disease
Chapter 92: Acquired Cystic Kidney Disease and Malignant Neoplasms
Chapter 93: Geriatric Nephrology
Chapter 94: Palliative Nephrology
Chapter 95: Approach to Kidney Replacement Therapy
Chapter 96: Vascular Access for Hemodialysis
Chapter 97: Diagnostic and Interventional Nephrology
Chapter 98: Hemodialysis: Principles and Techniques
Chapter 99: Hemodialysis: Dialysis Prescription and Adequacy
Chapter 100: Acute Complications During Hemodialysis
Chapter 101: Peritoneal Dialysis: Principles, Techniques, and Adequacy
Chapter 102: Complications of Peritoneal Dialysis
Chapter 103: Extracorporeal Therapies for Drug Overdose and Poisoning
Chapter 104: Plasma Exchange
Chapter 105: Immunologic Principles in Kidney Transplantation
Chapter 106: Immunosuppressive Medications in Kidney Transplantation
Chapter 107: Evaluation and Preoperative Management of Kidney Transplant Recipient and Donor
Chapter 108: Kidney Transplantation Surgery
Chapter 109: Prophylaxis and Treatment of Kidney Transplant Rejection
Chapter 110: Infections and Malignancies in the Kidney Transplant Recipient
Chapter 111: Cardiovascular Disease and Metabolic Abnormalities in the Kidney Transplant Recipient
Chapter 112: Chronic Allograft Injury
Chapter 113: Recurrent Disease in Kidney Transplantation
Chapter 114: Outcomes of Kidney Transplantation: Identification, Measures, and Evaluation
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