Infection and Autoimmunity
by Naim Mahroum, Abdulla Watad, Yehuda Shoenfeld
3rd Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780323991308 |
| eText ISBN | 9780323991315 |
| Publisher | Academic Press |
| Publishing Year | 2024 |
| Edition | 3rd Edition |
| Language | English |
| Pages | 1118 |
Infection and Autoimmunity, 3rd Edition delivers an extensive examination of the biological relationships connecting microbial exposure with autoimmune pathologies. Published by Academic Press, this volume provides medical students, researchers, academic staff, and basic scientists in immunology and rheumatology with a grounded theoretical framework. It analyzes how environmental microbial encounters interact with host immune responses to initiate or exacerbate disease processes.
The text structures its core coverage around major mechanistic pathways of immune dysregulation. It details how molecular mimicry and epitope spreading drive cross-reactive responses, while evaluating the regulatory role of the gut microbiota in systemic immunity. Additional sections address the immunological impact of vaccination, examining how immunizations interact with host tolerance mechanisms in clinical settings.
This edition incorporates 52 updated chapters detailing recent scientific developments in pathogen-host interactions. A key inclusion is dedicated coverage analyzing the correlation between SARS-CoV-2 infection and subsequent autoimmune responses. The volume offers targeted material suitable for advanced biomedical coursework and academic research focused on pathogen-induced autoimmunity.
Table of Contents
Chapter 1: Introduction
Chapter 2: Molecular Mimicry and Autoimmunity
Chapter 3: Epitope Spreading in Autoimmune Diseases
Chapter 4: The immune neuroendocrine system, infections, and rheumatic diseases
Chapter 5: CD5-Expressing B-1 Cells and Infection
Chapter 6: Lymphocytes and Infection in Autoimmune Diseases
Chapter 7: Endothelial Cell Autoreactivity and Infection
Chapter 8: Microbiota and Autoimmunity
Chapter 9: Infection, Autoimmunity, and Vitamin D
Chapter 10: Seasonality and Autoimmunity
Chapter 11: The Protective Role of Helminths in Autoimmunity
Chapter 12: Vaccination and Autoimmunity
Chapter 13: BCG Vaccination
Chapter 14: Opportunistic Infections and Autoimmune Diseases
Chapter 15: Can Antibiotics Cure Autoimmune Diseases?
Chapter 16: Anti-Viral Therapy, Epstein–Barr Virus, Autoimmunity, and Chaos (The Butterfly Effect)
Chapter 17: Roles for Cytomegalovirus in Infection, Inflammation, and Autoimmunity
Chapter 18: Hepatitis C and Mixed Cryoglobulinemia: An Update
Chapter 19: HIV Spectrum and Autoimmune Diseases
Chapter 20: Parvovirus Infection and Its Association with Autoimmune Diseases
Chapter 21: Human T-lymphotropic Virus Type 1 and Rheumatic Diseases: A Link Between Infection and Autoimmunity
Chapter 22: Sjögren’s Syndrome: Role of Viruses and Viral-Like Sequences
Chapter 23: Viral Infection and Heart Disease: Autoimmune Mechanisms
Chapter 24: Celiac Disease and Rotavirus Infection
Chapter 25: Theiler’s Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity
Chapter 26: Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease
Chapter 27: Helicobacter pylori Infection and Gastric Autoimmunity: Coincidence or a Cause and Effect Relationship?
Chapter 28: Multiple Sclerosis and Creutzfeldt–Jakob Disease are Autoimmune Diseases Probably Caused by Exposure to the Nasal Microbe Acinetobacter
Chapter 29: Infection and Autoimmunity in Antibiotic-Refractory Lyme Arthritis
Chapter 30: Streptococcus Pneumoniae and Autoimmunity: A Systematic Review of the Literature: How Pneumococcal Infection Might Be Related to Rheumatic Diseases
Chapter 31: Mycobacteria and Autoimmunity
Chapter 32: Mycobacterium avium Subspecies Paratuberculosis and Human Disease: Bridging Infection and Autoimmunity
Chapter 33: Leprosy and Autoimmunity
Chapter 34: Parasitic Infection and Autoimmunity
Chapter 35: Toxoplasma and Autoimmunity
Chapter 36: Malaria and Systemic Lupus Erythematosus: Complex Interactions and Reciprocal Influences
Chapter 37: Anti-Saccharomyces cerevisiae Antibodies Autoimmune Diseases
Chapter 38: The Infectious Origin of the Anti-Phospholipid Syndrome
Chapter 39: Infections and Systemic Lupus Erythematosus
Chapter 40: Infections and Idiopathic Inflammatory Myopathies
Chapter 41: Rheumatoid Arthritis and Infections: More Than an Association?
Chapter 42: Infection and Systemic Sclerosis
Chapter 43: Infection and Spondyloarthropathies
Chapter 44: Infection and Behçet Disease
Chapter 45: Vasculitides and Hepatitis C Infection
Chapter 46: The Role of Infection in Inflammatory Bowel Disease: Initiation, Exacerbation and Protection
Chapter 47: Post-Infectious Arthritis and Reactive Arthritis
Chapter 48: Infection and Autoimmune Liver Diseases
Chapter 49: The Role of infection in Immune-mediated Thrombocytopenia
Chapter 50: Viral Infections and Type 1 Diabetes
Chapter 51: Infection and Autoimmune Thyroid Diseases
Chapter 52: Pemphigus and Infection
Chapter 53: Infections and Autoimmune Renal Diseases
Chapter 54: Infections Associated with Retinal Autoimmunity
Chapter 55: Oral Infections and Autoimmune Diseases
Chapter 56: infection and Guillain–Barré Syndrome
Chapter 57: Acute Disseminated Encephalomyelitis
Chapter 58: COVID-19 and autoimmunity
Chapter 59: COVID-19 and autoantibodies
Chapter 60: COVID-19 and vasculitis
Chapter 61: COVID-19 vaccines and autoimmunity
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