Mitochondrial Signaling and Regulation

The 1st Edition of Mitochondrial Signaling and Regulation: Immune Responses and Diseases, edited by Seyyed Shamsadin Athari and Entezar Mehrabi Nasab, is a book examining organelle mechanics in cellular pathology. Published by Academic Press in 2025, this work examines how mitochondrial regulation influences cell signaling pathways and immune responses in disease pathogenesis.

The text structures its initial technical coverage around foundational organelle dynamics before systematically evaluating programmed cell death pathways across physiological conditions. Early chapters discuss mitochondrial biogenesis, fission and fusion, signaling pathways, and organelle crosstalk. Subsequent sections detail processes of mitophagy, autophagy, apoptosis, and necrosis associated with mitochondria to explain organelle regulatory mechanics.

To address therapeutic applications, the publication covers the use of biotechnology to develop new treatments and targeted therapies for mitochondrial dysfunction. By linking fundamental organelle operations to modern medical interventions, the material provides a systematic academic framework for evaluating cellular bioenergetics across pathological contexts.