Molecular Biology of B Cells
by Tasuku Honjo, Michael Reth, Andreas Radbruch, Frederick Alt, Alberto Martin
3rd Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780323958950 |
| eText ISBN | 9780323958967 |
| Publisher | Academic Press |
| Publishing Year | 2024 |
| Edition | 3rd Edition |
| Language | English |
| Pages | 548 |
Molecular Biology of B Cells, 3rd Edition, is a reference volume that presents updated research on B cell development and cellular function. The text provides an integrated view of normal immune responses alongside the molecular basis of diseases caused by B cell abnormalities, describing developmental and stimulatory processes in molecular, immunological, and genetic terms.
The volume details how B lymphocytes are generated, selected, activated, and engaged in antibody production across various stages of immune activity. It covers fundamental genetic processes underlying antigen receptor assembly, focusing specifically on the evolution, regulation, and molecular mechanism of V(D)J recombination. The text also explains how somatic hypermutation and activation-induced cytidine deaminase alter gene sequences.
Focusing on cellular maturation, the reference details memory B cells, plasma cells, and autoantibodies to illustrate how humoral memory and autoimmune reactivity function. This structural organization provides analytical support for researchers, scientists, clinicians, and graduate students who examine cellular pathways and pathological manifestations.
Table of Contents
Chapter 1: The Structure and Regulation of the Immunoglobulin Loci
Chapter 2: The Mechanism, Regulation and Evolution of V(D)J Recombination
Chapter 3: The Origin of V(D)J Diversification
Chapter 4: The Variable Lymphocyte Receptor B System of the Jawless Vertebrates
Chapter 5: Structure and Signalling Function of the B-Cell Antigen Receptor and Its Coreceptors
Chapter 6: Fc Receptors
Chapter 7: Transcriptional Regulation of Early B-Cell Development
Chapter 8: Relationship between B-Cell Populations, Development and Function of B-Cell Subsets
Chapter 9: B-Cell Development to Immunity and Tolerance
Chapter 10: The Role of the BAFF and Lymphotoxin Pathways in B Cell Biology
Chapter 11: Mechanism and Regulation of Immunoglobulin Class Switch Recombination
Chapter 12: Somatic Hypermutation
Chapter 13: Molecular Mechanism of Activation-Induced Cytidine Deaminase
Chapter 14: Molecular Pathogenesis of B-Cell Lymphomas
Chapter 15: Human Immunodeficiencies Caused by Inborn Errors of B-Cell Development or Function
Chapter 16: Memory B Cells and Plasma Cells
Chapter 17: Homoeostatic Versus Pathogenic Autoantibodies: Origin, Structure and Effector Functions
Chapter 18: Anti-Tumour Necrosis Factor and New Paradigms for Therapies Using Antibodies
Chapter 19: Therapeutic Targeting of B Cells and Plasma Cells with a Focus on Multiple Sclerosis and Other Autoimmune Conditions
Chapter 20: IMGT Immunoglobulin Repertoire Analysis and Antibody Humanization
Chapter 21: Mucosal Immunity to Bacteria and Immunoglobulin A Synthesis
Chapter 22: B-Cell Metabolism
Customer Reviews
0.0
0 reviews
No reviews yet. Be the first to review this book!
Write a Review
Reviewed by GradeFocus Editorial Team
▶Research Sources (14)
- Molecular Biology of B Cells - 3rd Edition - Elsevier Shop
- Molecular Biology of B Cells, eBook by Tasuku Honjo ... - Booktopia
- https://worldcat.org/isbn/9780323958967
- Molecular Biology of B Cells - E-bok (9780323958967) | Adlibris ...
- Molecular biology of B cells - ECU Libraries Catalog
- Molecular Biology of B Cells - RMIT University
- Molecular Biology of B Cells (ebook) | 9780323958967 | Livres | bol
- Please verify you are human - Captcha
- Untitled
- Molecular Biology of B Cells - ScienceDirect.com
- MOLECULAR BIOLOGY OF B CELLS 3ED (HB 2024) by HONJO T - Biblio
- Molecular Biology of B Cells (Third edition.) - Browns Books
- Molecular Biology Of B Cells 3Rd Edition 2024 By Honjo T - Atithi Books
- Molecular Biology of B Cells - ISBN 9780323958950 - Campusbooks.com
