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Systemic Lupus Erythematosus cover

Systemic Lupus Erythematosus

Basic, Applied and Clinical Aspects

by George C. Tsokos

3rd Edition

Publisher: Academic Press

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Book Details

Print ISBN9780443339578
eText ISBN9780443339585
PublisherAcademic Press
Publishing Year2026
Edition3rd Edition
LanguageEnglish

Systemic Lupus Erythematosus, 3rd Edition, presents a scientific and clinical reference covering the biological foundations and management of systemic lupus erythematosus. Published by Academic Press, this volume provides basic scientists, clinicians, rheumatologists, dermatologists, nephrologists, immunologists, and allergists with systematic information regarding disease mechanisms and medical care.

The text synthesizes major thematic areas including disease epidemiology, diagnostic criteria, underlying pathogenesis, pathways of tissue damage, clinical manifestations, and treatment options. It details the specific cellular, molecular, genetic, and environmental factors that instigate and drive systemic lupus erythematosus across human tissue systems and physiological pathways.

As a multi-specialty medical volume, the text functions as an essential reference work for hospital libraries supporting clinical staff and academic research personnel. It connects fundamental immunological research directly to clinical practice for specialists managing complex autoimmune diseases.

Table of Contents

  1. Chapter 1: Introduction

  2. Chapter 2: The patient

  3. Chapter 3: Practicing law with lupus: the story of a patient

  4. Chapter 4: Epidemiology

  5. Chapter 5: Measuring disease activity

  6. Chapter 6: Disease development and outcome

  7. Chapter 7: Socioeconomic aspects of SLE

  8. Chapter 8: Biomarkers in systemic lupus erythematosus

  9. Chapter 9: Biomarkers in lupus nephritis

  10. Chapter 10: Overview of the pathogenesis of systemic lupus erythematosus

  11. Chapter 11: System lupus erythematosus and the environment

  12. Chapter 12: Genes and genetics in human SLE

  13. Chapter 13: Monogenic lupus

  14. Chapter 14: Hormones

  15. Chapter 15: Clinical aspects of the complement system in systemic lupus erythematosus

  16. Chapter 16: T cells

  17. Chapter 17: B cells in SLE

  18. Chapter 18: Neutrophils in systemic lupus erythematosus

  19. Chapter 19: The role of dendritic cells in systemic lupus erythematosus

  20. Chapter 20: Platelets in lupus

  21. Chapter 21: Cytokines

  22. Chapter 22: RNA/DNA sensing in SLE—Toll-like receptors and beyond

  23. Chapter 23: The role of interferons in systemic lupus erythematosus

  24. Chapter 24: Fcγ receptors in autoimmunity and end organ damage

  25. Chapter 25: Apoptosis, autophagy, and necrosis

  26. Chapter 26: Infections in early systemic lupus erythematosus pathogenesis

  27. Chapter 27: Microbiota influences on systemic lupus erythematosus and Sjögren’s syndrome

  28. Chapter 28: Origin of autoantibodies

  29. Chapter 29: Anti-DNA antibodies

  30. Chapter 30: Antihistone and antispliceosome antibodies

  31. Chapter 31: Immune complexes in systemic lupus erythematosus

  32. Chapter 32: MicroRNA in systemic lupus erythematosus

  33. Chapter 33: Metabolic control of lupus pathogenesis

  34. Chapter 34: Epigenetics

  35. Chapter 35: What do mouse models and genetics teach us about human SLE?

  36. Chapter 36: Mechanisms of renal damage in systemic lupus erythematosus

  37. Chapter 37: Mechanisms of vascular damage in systemic lupus erythematosus

  38. Chapter 38: The mechanism of skin damage

  39. Chapter 39: Pathogenesis of tissue injury in the brain in patients with systemic lupus erythematosus

  40. Chapter 40: Constitutional symptoms and fatigue in systemic lupus erythematosus

  41. Chapter 41: The musculoskeletal system in SLE

  42. Chapter 42: Cutaneous lupus erythematosus

  43. Chapter 43: The clinical evaluation of kidney disease in systemic lupus erythematosus

  44. Chapter 44: The pathology of lupus nephritis

  45. Chapter 45: Cardiovascular disease in systemic lupus erythematosus: an update

  46. Chapter 46: The lung in systemic lupus erythematosus

  47. Chapter 47: Gastrointestinal, hepatic, and pancreatic disorders in systemic lupus erythematosus

  48. Chapter 48: Systemic lupus erythematosus and infections

  49. Chapter 49: Malignancies in systemic lupus erythematosus

  50. Chapter 50: The nervous system in systemic lupus erythematosus

  51. Chapter 51: Psychiatric lupus

  52. Chapter 52: Overlap syndromes

  53. Chapter 53: Systemic lupus erythematosus and the eye

  54. Chapter 54: Fertility and pregnancy in systemic lupus erythematosus

  55. Chapter 55: Neonatal lupus: Clinical spectrum, biomarkers, pathogenesis, and approach to treatment

  56. Chapter 56: Incomplete lupus syndromes

  57. Chapter 57: Lupus in children and adolescents

  58. Chapter 58: Drug-induced lupus

  59. Chapter 59: Vasculitis in lupus

  60. Chapter 60: Accrual of organ damage in lupus

  61. Chapter 61: Pathogenesis of antiphospholipid syndrome

  62. Chapter 62: Antibodies and diagnostic tests in antiphospholipid syndrome

  63. Chapter 63: Clinical manifestations

  64. Chapter 64: Nonsteroidal anti-inflammatory drugs in systemic lupus erythematosus

  65. Chapter 65: Value of antimalarial drugs in the treatment of lupus,

  66. Chapter 66: Systemic glucocorticoids

  67. Chapter 67: Cytotoxic drug treatment

  68. Chapter 68: Treatment of antiphospholipid syndrome

  69. Chapter 69: New treatments of systemic lupus erythematosus

  70. Chapter 70: Cell therapies in lupus

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▶Research Sources (18)
  • Systemic Lupus Erythematosus - 3rd Edition - Elsevier Shop
  • [PDF] Systemic Lupus Erythematosus by George C. Tsokos, 3rd ...
  • Systemic Lupus Erythematosus, eBook by George C. Tsokos | Basic ...
  • Immunopathogenesis print books and ebooks - Elsevier Shop
  • Systemic Lupus Erythematosus eBook de - EPUB | Rakuten Kobo ...
  • Systemic Lupus Erythematosus - Porrúa
  • Immunology print books and ebooks - page 2 | Elsevier | Elsevier Shop
  • Systemic Lupus Erythematosus (ebook) | 9780443339585 | Livres | bol
  • "Systemic Lupus Erythematosus" als eBook kaufen - Orell Füssli
  • Systemic lupus erythematosus
  • Systemic Lupus Erythematosus
  • Unmet medical needs in systemic lupus erythematosus - PMC
  • Systemic Lupus Erythematosus (SLE)
  • What is systemic lupus erythematosus (SLE)?
  • Systemic Lupus Erythematosus - MSK
  • A Comprehensive Review of Systemic Lupus Erythematosus
  • Systemic lupus erythematosus Fact Sheet
  • Chapter 21. Systemic Lupus Erythematosus - AccessMedicine

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