Biodegradable Metals and Their Medical Applications

Name: Biodegradable Metals and Their Medical Applications
Price: 235 USD
Availability: InStock
ISBN: 9780443221330

by Yufeng Zheng

1st Edition

Publisher: Elsevier

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Engineering

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Book Details

Print ISBN	9780443221330
eText ISBN	9780443221347
Publisher	Elsevier
Publishing Year	2025
Edition	1st Edition
Language	English

Biodegradable Metals and Their Medical Applications, 1st Edition, offers a structured technical overview of temporary metallic biomaterials and their practical biomedical implementations. Written to guide current engineering practice, the text outlines primary criteria, definitions, and classifications for selecting degradable metallic elements that dissolve within physiological environments.

The principal thematic arcs synthesize research on magnesium-based, iron-based, and zinc-based alloy systems, examining both base compositions and specialized biodegradable metal-matrix composites. It further investigates biodegradable bulk metallic glasses while detailing how 3D printing technologies are applied directly to magnesium, iron, and zinc alloys to fabricate complex medical constructs.

The text extends to specialized micro-scale technologies, discussing thin films of biodegradable metals integrated into transient electronic devices. It concludes by presenting emerging directions such as shape memory effects and the utilization of biodegradable metals as therapeutic drugs, serving as a focused resource for advanced students, engineers, researchers, and R&D professionals.

Chapter 1: Definition, criteria and classification of biodegradable metals
- • 1.1 Definition of biodegradable metals
- • 1.2 Criteria for being biodegradable metals
- • 1.2.1 Biodegradability criteria
- • 1.2.2 Biocompatibility criteria
- • 1.3 Classification of biodegradable metals
- • 1.4 General guidance on material design of biodegradable metals
Chapter 2: Mechanical bioadaptability of biodegradable metals
- • 2.1 Stress-strain behaviour of biodegradable metals under static load
- • 2.1.1 Tension
- • 2.1.2 Compression
- • 2.1.3 Torsion
- • 2.2 Stress-strain behaviour of biodegradable metals under dynamic load
- • 2.2.1 Fatigue in air
- • 2.2.2 Corrosion fatigue in simulated body fluid
- • 2.3 Mechanical property degeneration with time in vivo
- • 2.3.1 Mechanical property degeneration within bone
- • 2.3.2 Mechanical property degeneration within blood vessel
Chapter 3: Chemical bioadaptability of biodegradable metals
- • 3.1 Degradation mode and rate
- • 3.2 Modelling the degradation behaviour of biodegradable metals
- • 3.3 Controlling/coupling the degradation behaviour of biodegradable metals
- • 3.4 Conceptual idea on “100% completely biodegradable” metals
Chapter 4: Biological bioadaptability of biodegradable metals
- • 4.1 Metal ions and their bio-functions
- • 4.1.1 metal cations stimulate skeleton interoception
- • 4.1.2 metal ion metabolism in cardiovascular diseases
- • 4.1.3 metal ions and the antibacterial function
- • 4.2 Bioactivity of biodegradable metals and their bioactivity degree
- • 4.3 Biological property degeneration with time in vivo
Chapter 5: Mg-based biodegradable metals
- • 5.1 Material design and manufacture of biodegradable Mg alloy
- • 5.2 State-of-the-art of the Mg-based biodegradable metals
- • 5.2.1 high purity Mg
- • 5.2.2 Mg–Ca based alloys
- • 5.2.3 Mg–Sr-based alloys
- • 5.2.4 Mg–Zn-based alloys
- • 5.2.5 Mg–Si-based alloys
- • 5.3. State-of-the-art of the Mg-based biodegradable alloy device research
- • 5.3.1. Cardiovascular devices
- • 5.3.2. Orthopedic devices
- • 5.3.3 Other devices
- • 5.4. Challenges and opportunities for Mg-based biodegradable metals
Chapter 6: Fe-based biodegradable metals
- • 6.1 Material design and manufacture of biodegradable Fe alloy
- • 6.2 State-of-the-art of the Fe-based biodegradable metals
- • 6.2.1 High purity Fe
- • 6.2.2 Fe–Mn based alloys
- • 6.2.3 Nitride Fe
- • 6.3. State-of-the-art of the Fe-based biodegradable metal device research
- • 6.4. Challenges and opportunities for FE-based biodegradable metals
Chapter 7: Zn-based biodegradable metals
- • 7.1 Material design and manufacture of biodegradable Zn alloy
- • 7.2 State-of-the-art of the Zn-based biodegradable metals
- • 7.2.1 High purity Zn
- • 7.2.2 Zn–Mg based alloys
- • 7.2.3 Zn–Mn-based alloys
- • 7.2.4 Zn–Fe-based alloys
- • 7.2.5 Zn–Li-based alloys
- • 7.3. State-of-the-art of the Zn-based biodegradable alloy device research
- • 7.3.1. Cardiovascular devices
- • 7.3.2. Orthopedic devices
- • 7.3.3 Dental devices
- • 7.4. Challenges and opportunities for Zn-based biodegradable metals
Chapter 8: Surface treatment of biodegradable metals
- • 8.1 Mechanical treatment
- • 8.2 Physical treatment
- • 8.3 Chemical treatment
- • 8.4 Vitalizing treatment
Chapter 9: biodegradable metals matrix composites
- • 9.1 Material design and manufacture of biodegradable metals matrix composite
- • 9.2 Mg-based biodegradable metals matrix composites
- • 9.3 Fe-based biodegradable metals matrix composites
- • 9.4 Zn-based biodegradable metals matrix composites
Chapter 10: biodegradable bulk metallic glasses
- • 10.1 Material design and manufacture of biodegradable bulk metallic glass
- • 10.2 Mg-based biodegradable bulk metallic glasses
- • 10.3 Ca-based biodegradable bulk metallic glasses
- • 10.4 Zn-based biodegradable bulk metallic glasses
- • 10.5 Sr-based biodegradable bulk metallic glasses
Chapter 11: 3D printing of biodegradable metals
- • 11.1 Geometric design
- • 11.2 Powder fabrications
- • 11.3 3D printed Mg alloys
- • 11.4 3D printed Fe alloys
- • 11.5 3D printed Zn alloys
Chapter 12: thin films of biodegradable metals and their application in transient electronic devices
- • 12.1 Biodegradable magnesium related thin films
- • 12.2 Biodegradable molybdenum related thin films
- • 12.3 Biodegradable tungsten related thin films
- • 12.4 Biodegradable chromium related thin films
- • 12.5 Biodegradable iron related thin films
Chapter 13: Perspective on future development directions of biodegradable metals
- • 13.1 Usage of biodegradable metals as drugs
- • 13.2 Biodegradable metals with shape memory effects
- • 13.3 Activating biodegradable metals with external fields