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Medications for Older Persons cover

Medications for Older Persons

Recommendations, Harms, Evidence

by Roger E. Thomas

1st Edition

Publisher: Academic Press

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Book Details

Print ISBN9780443290251
eText ISBN9780443290268
PublisherAcademic Press
Publishing Year2025
Edition1st Edition
LanguageEnglish
Pages356

Medications for Older Persons, 1st Edition delivers a rigorous assessment of therapeutic benefits and adverse risks across senior pharmacotherapy. Designed primarily for clinicians caring for aging patients in community and hospital environments, this work investigates how specific prescribing choices contribute to adverse drug events, hospital readmissions, and patient mortality.

The publication organizes medical evidence across primary drug classes, including cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, and endocrine preparations, alongside pain management and fall prevention regimens. Each category is evaluated using randomized controlled trials with long follow-up periods, low risk of bias, and high GRADE quality, emphasizing precise Numbers Needed to Treat and Numbers Needed to Harm.

It incorporates established clinical screening tools such as STOPP and Beers criteria for potentially inappropriate medications, together with START criteria for potential prescribing omissions. This structured evidence base supports medical researchers identifying superior benefit-to-harm drug profiles and aids health ministry funders evaluating elder care interventions.

Table of Contents

  1. Chapter 1: A summary of medications that most benefit older patients: for clinicians, patients, their families, policy makers and health ministries

  2. Chapter 2: STOPP and American Geriatrics Society “potentially inappropriate medications" (PIMs) and START ”potential prescribing omissions” (PPOs)

  3. Chapter 3: The Calgary study of 295,706 admissions of older persons to four acute care hospitals 2013-2021

  4. Chapter 4: Adverse drug interactions in the Veterans Affairs Adverse Drug Event Reporting System

  5. Chapter 5: Pharmacokinetics and pharmacodynamics in older persons

  6. Chapter 6: Methods to identify adverse drug interactions and effects

  7. Chapter 7: How personalized medicine has changed senior patient outcomes at the Mayo Clinic and other centers

  8. Chapter 8: Older persons alcohol consumption

  9. Chapter 9: Self-medication and over the counter medications by older persons

  10. Chapter 10: The accuracy of recording medication lists, transferring lists between community practitioners and medical institutions, and the potential effects on the accuracy of assessing PIMs, PPOs and adverse medication events

  11. Chapter 11: Medications for hypertension

  12. Chapter 12: Medications for heart failure

  13. Chapter 13: Medications for arrhythmias

  14. Chapter 14: Medications for diuresis

  15. Chapter 15: Medications for coagulation

  16. Chapter 16: Medications for depression

  17. Chapter 17: Medications for anxiety

  18. Chapter 18: Medications for insomnia

  19. Chapter 19: Neuroleptic/antipsychotic medications

  20. Chapter 20: Avoiding medications with risks of delirium

  21. Chapter 21: Avoiding medications that augment dementia

  22. Chapter 22: Prescribing to reduce risks of renal insufficiency and failure

  23. Chapter 23: Prescribing to reduce the risks of peptic ulcer disease, gastritis, and esophagitis and treat if present

  24. Chapter 24: Prescribing to reduce the risks of constipation or diarrhea

  25. Chapter 25: Medications for arthritis

  26. Chapter 26: Medications for osteoporosis

  27. Chapter 27: Medications for COPD

  28. Chapter 28: Medications for diabetes

  29. Chapter 29: Non-opioid analgesics and opioids for seniors

  30. Chapter 30: Prescribing to prevent falls

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Reviewed by GradeFocus Editorial Team

▶Research Sources (15)
  • [PDF] Medications for Older Persons by Roger Thomas ... - Perlego
  • Academic Press print books and ebooks - page 111 | Elsevier ...
  • Medications for insomnia - Maastricht University
  • Medications for Older Persons - Roger Thomas - Bokklubben
  • Thompson Learn.
  • Please verify you are human - Captcha
  • Collection Updates December 2025 - Specialty Guides
  • Medications for Older Persons - 1st Edition - Elsevier Shop
  • Medications for Older Persons - ScienceDirect.com
  • Aging and Medications - Older People's Health - Merck Manuals
  • Medication Management for Older Adults | BeMedWise
  • Prescribing medicines to older people—How to consider the impact of ...
  • Medications for Older Persons ... | 9780443290251 - Ryefield Books
  • Common Medications for Older Adults - Healthy Aging - WebMD
  • Medication management in older adults | Cleveland Clinic Journal of ...

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