Ophthalmic Drug Delivery
Advancement, Industrialization Prospect and Applications
by Neelesh Kumar Mehra
1st Edition
Publisher: Academic Press
Book Details
| Print ISBN | 9780443337819 |
| eText ISBN | 9780443337826 |
| Publisher | Academic Press |
| Publishing Year | 2025 |
| Edition | 1st Edition |
| Language | English |
| Pages | 506 |
The 1st Edition of Ophthalmic Drug Delivery offers pharmaceutical scientists and corporate researchers an analytical guide to modern ocular therapeutic delivery. The text focuses on core formulation science, evaluating specialized platforms designed to transport active compounds across physiological barriers in the eye.
The volume details modern delivery approaches, evaluating the use of microneedles, hydrogels, and ocular inserts. These technical systems address specific ocular conditions, supporting therapeutic strategies for diseases such as glaucoma, age-related macular degeneration, uveal melanoma, cataracts, and fungal keratitis.
For product optimization, the text integrates systematic reverse engineering strategies alongside Quality by Design (QbD) applications. This technical framework provides practical direction for eyecare specialists and professionals in ocular therapeutics engaged in formulation development.
Table of Contents
Chapter 1: Introduction to Ocular Drug Delivery: Core Principles and Fundamental Concepts
Chapter 2: Complex ophthalmic Drug delivery Approaches
Chapter 3: Excipients and polymers in complex ophthalmic products: Formulation science and engineering perspectives
Chapter 4: Fixed-Dose Combination technique in ophthalmic products
Chapter 5: Emerging trends in ophthalmic products: Microneedles, hydrogels, and ocular inserts
Chapter 6: Reverse Engineering strategy in Complex Ophthalmic Product
Chapter 7: Quality by design and Design of Experiments (DOE) in Ophthalmic Product Development: Statistical Approaches and Optimization Strategies
Chapter 8: Translational roadmap for complex ophthalmic products
Chapter 9: Manufacturing Consideration, Scale-Up and Validation in Sterile Ophthalmic Formulation
Chapter 10: Safety Assessment and Toxicological Considerations of Nanocarriers in Ophthalmic Drug Delivery: Risk management, Animal Model and Preclinical Evaluation
Chapter 11: Advanced packaging, container and closure system for complex ophthalmic products
Chapter 12: Role of 3D Printing in Ophthalmic Products
Chapter 13: Stability Studies of Ophthalmic Product
Chapter 14: Regulatory Landscape of Ophthalmic Products
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