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Techno-Economic Modeling for Chemical and Bioprocess Innovations cover

Techno-Economic Modeling for Chemical and Bioprocess Innovations

by Chris Burk

1st Edition

Publisher: Wiley-Blackwell

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Engineering

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Book Details

Print ISBN9781394246410
eText ISBN9781394246427
PublisherWiley-Blackwell
Publishing Year2026
Edition1st Edition
LanguageEnglish
Pages358

Techno-Economic Modeling for Chemical and Bioprocess Innovations, 1st Edition, authored by Chris Burk and published by Wiley-Blackwell, is an academic textbook centered on developing techno-economic models within spreadsheets to assess economic drivers in chemical and bioprocess innovations. The volume establishes clear methods for converting chemical and biological process data into functional, dynamic financial spreadsheets.

Part I concentrates on essential spreadsheet construction standards. It presents systematic guidance on back-end data architecture, front-end user interface design, model documentation practices, and custom script implementation through Visual Basic for Applications (VBA). These chapters support learners in organizing raw data, input variables, and computational routines into stable calculation workbooks.

Part II expands into core modeling concepts, covering process diagrams, equipment sizing, process modeling, and equipment costing. Intended for upper-level engineering coursework, this 1st Edition provides practical frameworks for analyzing capital requirements and process viability across diverse technical applications.

Table of Contents

  1. Chapter 1: Introduction to Part I

    • • 1.1 Uses for Spreadsheets
    • • 1.2 Why Spreadsheets for TEM?
    • • 1.3 Alternative Techno-Economic Modeling Platforms
    • • 1.4 Importance of Good Spreadsheet Development Practices
    • • 1.5 Spreadsheet Development as Software Development
    • • 1.6 Back-End and Front-End Spreadsheet Development
    • • 1.7 Important Terms
    • • 1.8 Key Functions
    • • 1.9 Keyboard Shortcuts
    • • Reference
  2. Chapter 2: Back-End Development

    • • 2.1 Cell-Level Best Practices
    • • 2.2 Worksheet- and Workbook-Level Best Practices
  3. Chapter 3: Front-End Development

    • • 3.1 General Principles of User Interface Design
    • • 3.2 Cell-Level and Formatting Best Practices
    • • 3.3 Worksheet- and Workbook-Level Best Practices
    • • 3.4 User Interface Best Practices
    • • Reference
  4. Chapter 4: Documentation

    • • 4.1 Nearby Cells
    • • 4.2 Cell Notes
    • • 4.3 Dedicated Location Within Worksheet
    • • 4.4 Dedicated Worksheet
    • • 4.5 Separate Document
    • • 4.6 Screencast
    • • Reference
  5. Chapter 5: Visual Basic for Applications

    • • 5.1 VBA Basics
    • • 5.2 Working with VBA
    • • 5.3 Applications to TEM
    • • 5.4 AI-Assisted Coding
  6. Chapter 6: Introduction to Part II

    • • 6.1 Methods and Accuracy
    • • 6.2 Anatomy of a Techno-Economic Model
    • • Reference
  7. Chapter 7: Process Diagrams

    • • 7.1 Types and Use of Process Diagrams
    • • 7.2 Defining Model Scope
    • • 7.3 Best Practices
    • • 7.4 Concluding Thoughts
    • • References
  8. Chapter 8: Process Modeling

    • • 8.1 Spreadsheet Structure and Organization
    • • 8.2 The Stream Table
    • • 8.3 Material Balance Calculations
    • • 8.4 Energy Balance Calculations
    • • 8.5 Special Topics
    • • 8.6 Development Workflow
    • • Reference
  9. Chapter 9: Equipment Sizing

    • • 9.1 Spreadsheet Structure and Organization
    • • 9.2 Utility Calculations
    • • 9.3 Sizing Calculations
    • • 9.4 Materials of Construction
    • • 9.5 Development Workflow
    • • References
  10. Chapter 10: Equipment Costing

    • • 10.1 Structure and Organization
    • • 10.2 Power-Law Scaling
    • • 10.3 Factors for Adjusting Purchase Cost
    • • 10.4 Installation Factors
    • • 10.5 Putting It All Together
    • • 10.6 Development Workflow
    • • References
  11. Chapter 11: Capital Cost Estimation

    • • 11.1 Important Distinctions
    • • 11.2 Methods for Estimating Fixed Capital
    • • References
  12. Chapter 12: Operating Costs and Revenue Estimation

    • • 12.1 Structure and Organization
    • • 12.2 Variable Operating Costs
    • • 12.3 Operating Labor Costs
    • • 12.4 Other Fixed Operating Costs
    • • 12.5 Revenue
    • • References
  13. Chapter 13: Economic Value Estimation

    • • 13.1 Simple Metrics
    • • 13.2 Time Value of Money and Discounting
    • • 13.3 Levelized Cost
    • • 13.4 Cash Flow Analysis
    • • 13.5 Discounted Metrics
    • • 13.6 Incremental Analysis
    • • References
  14. Chapter 14: The Dashboard

    • • 14.1 Dashboard Design
    • • 14.2 Best Practices
  15. Chapter 15: Top-Down Modeling

    • • 15.1 Top-Down Model Structure
    • • 15.2 Steps to Building a Top-Down Model
  16. Chapter 16: Model Review and Debugging

    • • References
  17. Chapter 17: Conclusion: Working with Uncertainty

    • • 17.1 Uncertainty in Process Design
    • • 17.2 Uncertainty in the Model Inputs
  18. Chapter 18: Analysis Methods

    • • 18.1 Cost Distribution Charts
    • • 18.2 Basic Sensitivity Analyses
    • • 18.3 Tornado Diagrams
    • • 18.4 Monte Carlo Method
    • • 18.5 Scenario Analysis
    • • Reference
  19. Chapter 19: Techno-Economic Analysis in Practice

    • • 19.1 Assessing Potential for Economic Viability
    • • 19.2 Assessing Risk and Uncertainty
    • • 19.3 Guiding R&D
    • • 19.4 Communication
  20. Chapter 20: Bottom-Up Case Study

    • • 20.1 Process Description
    • • 20.2 Model Walkthrough
    • • 20.3 Model Review
    • • 20.4 Analysis and Discussion
    • • References
  21. Chapter 21: Top-Down Case Study

    • • 21.1 Process Description
    • • 21.2 Model Walkthrough
    • • 21.3 Model Review: Comparison with Study Results
    • • 21.4 Analysis and Discussion
    • • References

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▶Research Sources (14)
  • Techno-Economic Modeling for Chemical and Bioprocess ...
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  • Techno-Economic Modeling for Chemical and
  • Techno-Economic Modeling for Chemical & Bioprocess ...
  • Techno-economic modeling for chemical and bioprocess ...
  • Techno-Economic Analysis for Hard-Tech Innovation
  • Techno Economic Process Modeling Consulting
  • Techno-economic and Life-cycle Modeling

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