Haemoglobinopathy Diagnosis

Haemoglobinopathy Diagnosis, 4th Edition, by Barbara J. Bain and David C. Rees, is an authoritative reference work focused on the laboratory diagnosis of haemoglobin disorders. Published by Wiley-Blackwell, the text addresses essential clinical laboratory workflows by detailing the selection, performance, and interpretation of tests offered by diagnostic laboratories.

The analytical scope connects basic genetic mechanisms with complex diagnostic testing. The authors detail the underlying genetics of haemoglobin synthesis alongside specific laboratory techniques for globin chain synthesis identification. Subsequent thematic sections systematically review thalassaemias and related conditions, sickle cell haemoglobin, and the distinct diagnostic findings produced by interactions of sickle cell with thalassaemias and variant haemoglobins.

To support practical instruction and analytical evaluation, the volume includes dedicated self-assessment case studies designed for trainees. This content establishes targeted clinical reference support for trainees in haematology as well as practicing haematologists operating across clinical laboratory settings.