Transfusion Medicine and Hemostasis
Clinical and Laboratory Aspects
by Beth H. Shaz, Christopher D. Hillyer, Joseph (Yossi) Schwartz, Morayma Reyes Gil
4th Edition
Publisher: Elsevier Science
Book Details
| Print ISBN | 9780323960144 |
| eText ISBN | 9780323960151 |
| Publisher | Elsevier Science |
| Publishing Year | 2024 |
| Edition | 4th Edition |
| Language | English |
| Pages | 890 |
Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects, 4th Edition, edited by Beth H. Shaz, Christopher D. Hillyer, Joseph (Yossi) Schwartz, and Morayma Reyes Gil, is a pocket-sized reference published by Elsevier Science. This volume offers concise guidance on routine practices and emerging clinical topics across blood banking and coagulation assessment.
The text organizes clinical coverage around blood donor collection, component manufacturing, quality principles, and regulatory considerations. Readers find structured details on recipient-specific blood donations, serologic testing of donor products, and pretransfusion testing procedures. Additional sections outline therapeutic applications for mononuclear cell products, platelet-rich plasma, and cellular therapies including CAR-T cells.
Selected as a 2025 Doody's Core Title in Laboratory Medicine, this reference serves as a practical tool during clinical rotations and bench evaluations. The publication supports pathology residents, medicine residents, surgery residents, and anesthesia residents alongside hematology fellows seeking rapid clinical direction.
Table of Contents
Chapter 1: Blood banking and transfusion medicine – the field, the discipline and the industry
Chapter 2: Quality principles in Transfusion medicine
Chapter 3: Regulatory issues in transfusion medicine
Chapter 4: Role of the physician in the blood center
Chapter 5: Blood donor, donation process and technical aspects of blood collection
Chapter 6: Apheresis blood component collections
Chapter 7: Recipient-specific blood donations
Chapter 8: Adverse donor reactions (iron)
Chapter 9: Component preparation and manufacturing
Chapter 10: Serologic testing of donor products
Chapter 11: Overview of infectious disease testing
Chapter 12: HIV screening
Chapter 13: Hepatitis B screening
Chapter 14: Hepatitis C screening
Chapter 15: WNV screening
Chapter 16: Zika screening
Chapter 17: Babesia screening
Chapter 18: Syphilis, HTLV and Chagas screening
Chapter 19: Bacterial mitigation of platelets
Chapter 20: Role of the transfusion service physician
Chapter 21: Pretransfusion testing
Chapter 22: Antibody identification
Chapter 23: Direct antiglobulin test
Chapter 24: Molecular DNA based blood group typing
Chapter 25: ABO and H blood group systems
Chapter 26: RH and RhAg blood group system
Chapter 27: KELL and KIDD blood group systems
Chapter 28: MNS AND DUFFY blood group systems
Chapter 29: LEWIS, I P1Pk and Glob blood group systems
Chapter 30: Other blood group systems, collections, and antigens
Chapter 31: Human platelet and neutrophil antigens
Chapter 32: HLA Antigens
Chapter 33: Red blood cells products
Chapter 34: Plasma products
Chapter 35: Platelet products (to include PAS if not previously mentioned; was mentioned In the 2nd edition)
Chapter 36: Cryoprecipitate and fibrinogen concentrates
Chapter 37: Granulocyte products
Chapter 38: Albumin and related products
Chapter 39: Human immunoglobuin preparations
Chapter 40: Rh immune globulin
Chapter 41: Coagulation Factor products
Chapter 42: Platelet rich plasma
Chapter 43: Convalescent plasma, including COVID convalescent plasma
Chapter 42: Nonfactor therapies for bleeding disorders
Chapter 44: Blood Pharming and alternative blood production methods
Chapter 45: Irradiation of blood products
Chapter 44: Leukoreduction of blood products
Chapter 46: CMV-safe blood products
Chapter 47: Frozen blood products
Chapter 48: Washed blood products
Chapter 49: Volume reduced blood products
Chapter 50: Pathogen reduction technologies
Chapter 51: Intrauterine, Neonatal and pediatric transfusion medicine
Chapter 52: Perinatal transfusion medicine
Chapter 53: AutoImmune hemolytic anemias
Chapter 54: Transfusion management in patients with hemoglobinopathies
Chapter 55: Transfusion of Patients Undergoing Hematopoietic Stem Cell Transplantation
Chapter 56: Transfusion of Patients Undergoing Solid Organ Transplantation
Chapter 57: Transfusion support and hemostatic monitoring in patients connected to extracorporeal devices
Chapter 58: Transfusion of patients receiving antithrombotic therapy
Chapter 59: Blood transfusion in economically restricted and developing countries
Chapter 60: Management of Patients Who Refuse Blood Transfusion
Chapter 61: Platelet transfusion refractory patients
Chapter 62: Massive transfusion
Chapter 63: Patient blood management
Chapter 64: Overview of adverse events and outcomes following transfusion
Chapter 65: Febrile non-hemolytic transfusion reactions
Chapter 66: Allergic transfusion reactions
Chapter 67: Acute hemolytic transfusion reactions
Chapter 68: Delayed hemolytic transfusion reactions
Chapter 69: Transfusion-Associated Circulatory Overload
Chapter 70: Transfusion-Related Acute Lung Injury
Chapter 71: Septic transfusion reactions
Chapter 72: Metabolic, hypotensive and other acute reactions and complications
Chapter 73: Post transfusion purpura
Chapter 74: Transfusion associated graft versus host disease
Chapter 75: Transfusion related immunomodulation
Chapter 76: Iron Overload
Chapter 77: Transfusion transmitted diseases
Chapter 78: Overview to therapeutic apheresis
Chapter 79: Therapeutic plasma exchange
Chapter 80: Therapeutic erythrocytapheresis
Chapter 81: Therapeutic thrombocytapheresis
Chapter 82: Therapeutic leukocytapheresis and adsorptive cytapheresis
Chapter 83: Extracorporeal photopheresis
Chapter 84: LDL apheresis
Chapter 85: Immunoabsorption
Chapter 86: COVID-19 & Apheresis
Chapter 87: Therapeutic phlebotomy
Chapter 88: Overview of cellular therapy
Chapter 89: HPC products derived from bone marrow and peripheral blood
Chapter 90: Cord blood banking (expansion)
Chapter 91: Regenerative medicine (iPS)
Chapter 92: Immunotherpy (T cells): CAR-T, TILs, gene therapy and more
Chapter 93: Adverse events associated with HPC product infusion
Chapter 94: Quality and regulatory issues in cellular therapy
Chapter 95: Tissue banking in the hospital setting
Chapter 96: Overview of the coagulation system
Chapter 97: Approach to the patient with a bleeding disorder
Chapter 98: Congenital thrombocytopenia
Chapter 99: fetal and Neonatal alloimmune thrombocytopenia
Chapter 100: Acquired neonatal thrombocytopenia
Chapter 101: Bernard Soulier syndrome and other GPIb-IX-V related receptor defects
Chapter 102: Glanzmann's thrombocytopenia
Chapter 103: Other platelet glycoprotein disorders
Chapter 104: Platelet storage-granule defects
Chapter 105: Failure to release and aspirin-like defects
Chapter 106: Other Platelet abnormalities
Chapter 107: Acquired platelet disorders
Chapter 108: Acute (childhood) ITP
Chapter 109: Chronic ITP
Chapter 110: Drug induced thrombocytopenia
Chapter 111: Heparin induced thrombocytopenia
Chapter 112: Vaccine Induced Thrombotic Immune Thrombocytopenia
Chapter 113: Autoimmune lymphoproliferative syndrome
Chapter 114: Hemolytic uremic syndrome
Chapter 115: Thrombotic thrombocytopenic purpura
Chapter 116: Antiphophospholipid syndrome
Chapter 117: Von Willebrand Disease
Chapter 118: Hemophilia A
Chapter 119: Hemophilia B
Chapter 120: Congenital disorders of fibrinogen
Chapter 121: Factor XIII, D α2-Antiplasmin, and Plasminogen Activator Inhibitor-1 deficiencies
Chapter 122: Factor XI deficiency
Chapter 123: Factor VII deficiency
Chapter 124: Factor II, factor V, and factor X deficiencies
Chapter 125: Bleeding disorders in pregnancy
Chapter 126: Vascular bleeding disorders
Chapter 127: Hemostasis in Liver Disease
Chapter 128: Bleeding risks with Vitamin K deficiency
Chapter 129: Bleeding risks with cardiac disease
Chapter 130: Bleeding risks with renal disease
Chapter 131: Bleeding risks with cancer
Chapter 132: Disseminated intravascular coagulopathy
Chapter 133: coagulopathy in sickle cell disease and other hemoglobiniopathies
Chapter 134: COVID coagulopathy
Chapter 135: Thrombosis in COVID Coagulopathy---Anticoagulation guidelines
Chapter 136: Bleeding in COVID coagulopathy
Chapter 137: Acquired coagulation factor inhibitors
Chapter 138: Overview of purposes of hemostasis testing and common sources of error
Chapter 139: Pediatric reference ranges in coagulation testing
Chapter 140: Prothrombin Time
Chapter 141: Activated Partial Thrombolplastin Time
Chapter 142: Mixing studies
Chapter 143: Coagulation Factor Testing
Chapter 144: Testing of Nonfactor therapies: emicizumab
Chapter 145: Testing of Nonfactor therapies: inhibitors of anticoagulant pathways (fitusiran and concizumab)
Chapter 146: Specific Factor Inhibitor Testing
Chapter 147: Thrombin time and Fibrinogen Evaluation
Chapter 148: laboratory diagnosis of inherited von Willebrand Disease
Chapter 149: Laboratory Diagnosis of Acquired von Willebrand’s Syndrome
Chapter 150: Laboratory Assessment of Treatment of von Willebrand’s Disease
Chapter 151: Measurement of platelet count, mean platelet volume, and reticulated platelets
Chapter 152: Platelet Function Analyzer
Chapter 153: thromboelastography/thromboelastometry
Chapter 154: Platelet Aggregation Studies
Chapter 155: Laboratory Diagnosis of Platelet Functional Defects
Chapter 156: Confirmatory testing for diagnosis of platelet disorders
Chapter 157: Platelets in COVID coagulopathy
Chapter 158: Anti-platelet Therapy Monitoring
Chapter 159: Laboratory evaluation of factor XIII deficiency
Chapter 160: Fibrinolytic testing
Chapter 161: Age-adjusted D-Dimer cut offs to rule out PE/ VTE
Chapter 162: Laboratory techniques in fibrinolysis testing
Chapter 163: Laboratory evaluation of long-term thrombophilic disorders
Chapter 164: Thrombophilia testing in children
Chapter 165: Antithrombin Testing
Chapter 166: Protein C deficiency evaluation
Chapter 167: Protein S deficiency evaluation
Chapter 168: testing for Activated Protein C Resistance
Chapter 169: Molecular Testing for Factor V Leiden and Prothrombin Gene Mutations in inherited thrombophilia
Chapter 170: Chronic elevated levels of Factor VIII and other coagulation factors
Chapter 171: Laboratory Monitoring for Heparins, fondaparinux, direct thrombin inhibitors, and oral anti-Xa medications
Chapter 172: DOAC interferences in coagulation testing
Chapter 173: Laboratory testing in patients receiving DOAC antidotes
Chapter 174: Laboratory support for warfarin monitoring
Chapter 175: Molecular testing in Coagulation
Chapter 176: Acquired prothrombotic conditions
Chapter 177: Ventricular assist device: anticoagulation monitoring
Chapter 178: Laboratory Evaluation of Heparin-Induced Thrombocytopenia
Chapter 179: Laboratory Evaluation of Thrombotic Thromcytopenic Purpura
Chapter 180: D-Dimer testing in COVID coagulopathy
Chapter 181: Other coagulation tests in COVID coagulopathy
Chapter 182: Laboratory diagnosis of lupus anticoagulant and anti-phopholipid antibodies
Chapter 183: Lupus anticoagulant testing in COVID-19
Chapter 184: Circulating microparticles
Chapter 185: Thrombin Generation Assays
Chapter 186: Laboratory testing of contact factors
Chapter 187: Contact factors and complements
Chapter 188: Monitoring of new anticoagulants---inhibitors of contact factors
Chapter 189: Reference ranges in transgender
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▶Research Sources (15)
- https://www.worldcat.org/isbn/9780323960151
- https://www.wob.com/en-us/search?term=9780323960151
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