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Kratom cover

Kratom

History, Science and Therapeutic Potential

by Jack E. Henningfield, Chad E. Beyer, Robert B. Raffa

1st Edition

Publisher: Academic Press

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Book Details

Print ISBN9780443274121
eText ISBN9780443274138
PublisherAcademic Press
Publishing Year2025
Edition1st Edition
LanguageEnglish
Pages262

Kratom: History, Science and Therapeutic Potential, 1st Edition, provides a comprehensive scientific analysis of Mitragyna speciosa for healthcare providers, general practitioners, and addiction researchers. The publication addresses critical knowledge needs surrounding the plant, focusing on its dual presentation of weak opioid and stimulant effects in contemporary settings.

The volume surveys the botanical features, geographic distribution, and phytochemistry of Mitragyna speciosa alongside its historical scientific evolution. It details chemical properties, primary metabolites, and ADME profiles while examining physical dependence and addiction mechanisms. The text also reviews evidence regarding potential therapeutic applications for depression, attention deficit hyperactivity disorder, post-traumatic stress disorder, and opioid use disorder.

By combining phytochemical data with clinical pharmacological perspectives, the book supports central nervous system drug developers and regulatory scholars evaluating botanical materials. This volume offers structured reference material to guide research, clinical inquiry, and evidence-based practice across related scientific disciplines.

Table of Contents

  1. Chapter 1: Botany, geographical distribution, and phytochemistry of Mitragyna speciosa(Korth.) and related species

  2. Chapter 2: The scientific evolution of kratom: a historical overview

  3. Chapter 3: Recent patterns and reasons for use

  4. Chapter 4: Chemistry and metabolites: ADME

  5. Chapter 5: Kratom-related physical dependence and addiction

  6. Chapter 6: Current therapeutic uses

  7. Chapter 7: Regulation and policy regarding kratom-derived dietary supplements and direct-to-consumer sales

  8. Chapter 8: Patentability and exclusivity of kratom based natural products

  9. Chapter 9: Kratom drug–drug (and other) interactions

  10. Chapter 10: Susceptible populations

  11. Chapter 11: Kratom purity and quality control issues: an in-depth analysis

  12. Chapter 12: Kratom entrepreneurship | exploiting the commercial potential of kratom and its active alkaloids

  13. Chapter 13: Equity investment into kratom, mitragynine, and related products

  14. Chapter 14: Medical marijuana as a template for understanding kratom

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▶Research Sources (15)
  • Kratom - 1st Edition
  • Kratom, eBook by Jack E. Henningfield | History, Science and ...
  • [PDF] Kratom by Jack E. Henningfield | 9780443274138
  • Kratom-related physical dependence and addiction
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  • Kratom: Uses, Dosage, Side Effects, Warnings
  • Kratom Use in ADHD: A Case Highlighting Stimulant and ...

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